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==Crystal structure of replisomal dimer of DNA polymerase from bacteriophage RB69 with DNA duplexes==
==Crystal structure of replisomal dimer of DNA polymerase from bacteriophage RB69 with DNA duplexes==
<StructureSection load='5gnq' size='340' side='right' caption='[[5gnq]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='5gnq' size='340' side='right'caption='[[5gnq]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5gnq]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GNQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GNQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[5gnq]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GNQ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5GNQ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DUP:2-DEOXYURIDINE+5-ALPHA,BETA-IMIDO-TRIPHOSPHATE'>DUP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DUP:2-DEOXYURIDINE+5-ALPHA,BETA-IMIDO-TRIPHOSPHATE'>DUP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gnq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gnq OCA], [http://pdbe.org/5gnq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gnq RCSB], [http://www.ebi.ac.uk/pdbsum/5gnq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gnq ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5gnq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gnq OCA], [http://pdbe.org/5gnq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gnq RCSB], [http://www.ebi.ac.uk/pdbsum/5gnq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gnq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DPOL_BPR69 DPOL_BPR69]] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.  
[[http://www.uniprot.org/uniprot/DPOL_BPR69 DPOL_BPR69]] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.  
==See Also==
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: DNA-directed DNA polymerase]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Large Structures]]
[[Category: An, J Y]]
[[Category: An, J Y]]
[[Category: Eom, S H]]
[[Category: Eom, S H]]

Revision as of 06:47, 13 May 2020

Crystal structure of replisomal dimer of DNA polymerase from bacteriophage RB69 with DNA duplexes

5gnq, resolution 2.10Å

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