EPSP synthase: Difference between revisions

'''5-enolpyruvylshikimate 3-phosphate (EPSP) synthase''' is a key enzyme for the biosynthesis of aromatic amino acids in plants and many microbes. EPSP synthase catalyzes the addition of phosphoenol pyruvate (PEP) to shikimate-3-phosphate (S3P), generating 5-enolpyruvylshikimate-3-phosphate, which is a precursor for phenylalanine and tyrosine<ref>PMID:16225867</ref>. EPSP synthase is a target for herbicides like '''Roundup''', which contain glyphosate, an inhibitor of EPSP synthase.  Herbicide resistant plants contain an glyphosate insensitive version of EPSP synthase derived from ''Agrobacterium'' sp strain CP4, so it is called CP4 EPSP synthase. <ref>PMID:16916934</ref>,