6b6i: Difference between revisions

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'''Unreleased structure'''


The entry 6b6i is ON HOLD  until Paper Publication
==2.4A resolution structure of human Norovirus GII.4 protease==
 
<StructureSection load='6b6i' size='340' side='right' caption='[[6b6i]], [[Resolution|resolution]] 2.44&Aring;' scene=''>
Authors: Muzzarelli, K.M., Kuiper, B.D., Spellmon, N.S., Hackett, J., Brunzelle, J.S., Kovari, I.A., Amblard, F., Yang, Z., Schinazi, R.F., Kovari, L.C.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6b6i]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B6I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B6I FirstGlance]. <br>
Description: 2.4A resolution structure of human Norovirus GII.4 protease
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b6i OCA], [http://pdbe.org/6b6i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b6i RCSB], [http://www.ebi.ac.uk/pdbsum/6b6i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b6i ProSAT]</span></td></tr>
[[Category: Unreleased Structures]]
</table>
[[Category: Kovari, I.A]]
== Function ==
[[Category: Spellmon, N.S]]
[[http://www.uniprot.org/uniprot/A0A076EGG6_9CALI A0A076EGG6_9CALI]] 3C-like protease processes the polyprotein: 3CLpro-RdRp is first released by autocleavage, then all other proteins are cleaved. May cleave polyadenylate-binding protein thereby inhibiting cellular translation.[PROSITE-ProRule:PRU00870]  
__TOC__
</StructureSection>
[[Category: Amblard, F]]
[[Category: Amblard, F]]
[[Category: Brunzelle, J S]]
[[Category: Hackett, J]]
[[Category: Kovari, I A]]
[[Category: Kovari, L C]]
[[Category: Kuiper, B D]]
[[Category: Muzzarelli, K M]]
[[Category: Schinazi, R F]]
[[Category: Spellmon, N S]]
[[Category: Yang, Z]]
[[Category: Yang, Z]]
[[Category: Schinazi, R.F]]
[[Category: 3c-like protease]]
[[Category: Muzzarelli, K.M]]
[[Category: Gii 4]]
[[Category: Brunzelle, J.S]]
[[Category: Minerva]]
[[Category: Hackett, J]]
[[Category: Protease]]
[[Category: Kovari, L.C]]
[[Category: Viral protease]]
[[Category: Kuiper, B.D]]
[[Category: Viral protein]]
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