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==A transition from strong right-handed to canonical left-handed supercoiling in a conserved coiled coil segment of trimeric autotransporter adhesins - the Mutant 4 structure==
==A transition from strong right-handed to canonical left-handed supercoiling in a conserved coiled coil segment of trimeric autotransporter adhesins - the Mutant 4 structure==
<StructureSection load='3lt6' size='340' side='right' caption='[[3lt6]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='3lt6' size='340' side='right'caption='[[3lt6]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3lt6]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_enterocoliticum"_schleifstein_and_coleman_1939 "bacterium enterocoliticum" schleifstein and coleman 1939]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LT6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LT6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3lt6]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_enterocolitica Yersinia enterocolitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LT6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LT6 FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3h7x|3h7x]], [[3h7z|3h7z]], [[3lt7|3lt7]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">yadA, invA, yop1, yopA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=630 "Bacterium enterocoliticum" Schleifstein and Coleman 1939])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lt6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lt6 OCA], [https://pdbe.org/3lt6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lt6 RCSB], [https://www.ebi.ac.uk/pdbsum/3lt6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lt6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lt6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lt6 OCA], [http://pdbe.org/3lt6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lt6 RCSB], [http://www.ebi.ac.uk/pdbsum/3lt6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3lt6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/YADA1_YEREN YADA1_YEREN]] Collagen-binding outer membrane protein forming a fibrillar matrix on the bacterial cell surface. Promotes initial attachment and invasion of eukaryotic cells. Also protects the bacteria by being responsible for agglutination, serum resistance, complement inactivation and phagocytosis resistance.<ref>PMID:2592347</ref>
[https://www.uniprot.org/uniprot/YADA2_YEREN YADA2_YEREN] Collagen-binding outer membrane protein forming a fibrillar matrix on the bacterial cell surface. Promotes initial attachment and invasion of eukaryotic cells. Also protects the bacteria by being responsible for agglutination, serum resistance, complement inactivation and phagocytosis resistance.<ref>PMID:12813066</ref> <ref>PMID:2592347</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lt/3lt6_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lt/3lt6_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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</div>
</div>
<div class="pdbe-citations 3lt6" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3lt6" style="background-color:#fffaf0;"></div>
==See Also==
*[[Adhesin 3D structures|Adhesin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacterium enterocoliticum schleifstein and coleman 1939]]
[[Category: Large Structures]]
[[Category: Hernandez-Alvarez, B]]
[[Category: Yersinia enterocolitica]]
[[Category: Lupas, A N]]
[[Category: Hernandez-Alvarez B]]
[[Category: Zeth, K]]
[[Category: Lupas AN]]
[[Category: Cell adhesion]]
[[Category: Zeth K]]
[[Category: Cell membrane]]
[[Category: Cell outer membrane]]
[[Category: Core residue]]
[[Category: Membrane]]
[[Category: Trimeric autotransporter]]
[[Category: Virulence]]
[[Category: Yada]]
Retrieved from "https://proteopedia.org/3lt6"