1zsn: Difference between revisions

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[[Image:1zsn.gif|left|200px]]
[[Image:1zsn.gif|left|200px]]


{{Structure
<!--
|PDB= 1zsn |SIZE=350|CAPTION= <scene name='initialview01'>1zsn</scene>, resolution 2.992&Aring;
The line below this paragraph, containing "STRUCTURE_1zsn", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TN2:5-CHLORO-2-(2-CHLORO-4-NITROPHENOXY)PHENOL'>TN2</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span>
or leave the SCENE parameter empty for the default display.
|GENE= PfENR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 Plasmodium falciparum])
-->
|DOMAIN=
{{STRUCTURE_1zsn| PDB=1zsn  | SCENE= }}  
|RELATEDENTRY=[[1nhd|1NHD]], [[1nhg|1NHG]], [[1nhw|1NHW]], [[1nnu|1NNU]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zsn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zsn OCA], [http://www.ebi.ac.uk/pdbsum/1zsn PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1zsn RCSB]</span>
}}


'''Synthesis, Biological Activity, and X-Ray Crystal Structural Analysis of Diaryl Ether Inhibitors of Malarial Enoyl ACP Reductase. Part 1:4'-Substituted Triclosan Derivatives'''
'''Synthesis, Biological Activity, and X-Ray Crystal Structural Analysis of Diaryl Ether Inhibitors of Malarial Enoyl ACP Reductase. Part 1:4'-Substituted Triclosan Derivatives'''
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==Reference==
==Reference==
Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-substituted triclosan derivatives., Freundlich JS, Anderson JW, Sarantakis D, Shieh HM, Yu M, Valderramos JC, Lucumi E, Kuo M, Jacobs WR Jr, Fidock DA, Schiehser GA, Jacobus DP, Sacchettini JC, Bioorg Med Chem Lett. 2005 Dec 1;15(23):5247-52. Epub 2005 Sep 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16198563 16198563]
Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-substituted triclosan derivatives., Freundlich JS, Anderson JW, Sarantakis D, Shieh HM, Yu M, Valderramos JC, Lucumi E, Kuo M, Jacobs WR Jr, Fidock DA, Schiehser GA, Jacobus DP, Sacchettini JC, Bioorg Med Chem Lett. 2005 Dec 1;15(23):5247-52. Epub 2005 Sep 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16198563 16198563]
[[Category: Enoyl-[acyl-carrier-protein] reductase (NADH)]]
[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: Shieh, H M.]]
[[Category: Shieh, H M.]]
[[Category: Yu, M.]]
[[Category: Yu, M.]]
[[Category: oxidoreductase]]
[[Category: Oxidoreductase]]
 
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