5dzy: Difference between revisions

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==Protocadherin beta 8 extracellular cadherin domains 1-4==
==Protocadherin beta 8 extracellular cadherin domains 1-4==
<StructureSection load='5dzy' size='340' side='right' caption='[[5dzy]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='5dzy' size='340' side='right'caption='[[5dzy]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5dzy]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DZY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DZY FirstGlance]. <br>
<table><tr><td colspan='2'>[[5dzy]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DZY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DZY FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dzv|5dzv]], [[5dzw|5dzw]], [[5dzx|5dzx]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Pcdhb8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dzy OCA], [https://pdbe.org/5dzy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dzy RCSB], [https://www.ebi.ac.uk/pdbsum/5dzy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dzy ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dzy OCA], [http://pdbe.org/5dzy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dzy RCSB], [http://www.ebi.ac.uk/pdbsum/5dzy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dzy ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PCDB8_MOUSE PCDB8_MOUSE] Calcium-dependent cell-adhesion protein involved in cells self-recognition and non-self discrimination (Probable). Thereby, it is involved in the establishment and maintenance of specific neuronal connections in the brain (PubMed:27161523).<ref>PMID:27161523</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lk3 transgenic mice]]
[[Category: Large Structures]]
[[Category: Bahna, F]]
[[Category: Mus musculus]]
[[Category: Goodman, K M]]
[[Category: Bahna F]]
[[Category: Honig, B]]
[[Category: Goodman KM]]
[[Category: Mannepalli, S]]
[[Category: Honig B]]
[[Category: Shapiro, L]]
[[Category: Mannepalli S]]
[[Category: Cadherin]]
[[Category: Shapiro L]]
[[Category: Cell adhesion]]
[[Category: Dimer]]
[[Category: Extracellular]]
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