4tlw: Difference between revisions

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==CARDS TOXIN, FULL-LENGTH==
==CARDS TOXIN, FULL-LENGTH==
<StructureSection load='4tlw' size='340' side='right' caption='[[4tlw]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
<StructureSection load='4tlw' size='340' side='right'caption='[[4tlw]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4tlw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycpn Mycpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TLW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TLW FirstGlance]. <br>
<table><tr><td colspan='2'>[[4tlw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycoplasma_pneumoniae_M129 Mycoplasma pneumoniae M129]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TLW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TLW FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4tlv|4tlv]]</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tlw OCA], [https://pdbe.org/4tlw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tlw RCSB], [https://www.ebi.ac.uk/pdbsum/4tlw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tlw ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MPN_372, MP464 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272634 MYCPN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tlw OCA], [http://pdbe.org/4tlw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4tlw RCSB], [http://www.ebi.ac.uk/pdbsum/4tlw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4tlw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CARDS_MYCPN CARDS_MYCPN]] Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells.<ref>PMID:16617115</ref>
[https://www.uniprot.org/uniprot/CARDS_MYCPN CARDS_MYCPN] Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells.<ref>PMID:16617115</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Mycpn]]
[[Category: Large Structures]]
[[Category: Becker, A]]
[[Category: Mycoplasma pneumoniae M129]]
[[Category: GALALELDEEN, A]]
[[Category: Becker A]]
[[Category: Hart, P J]]
[[Category: GALALELDEEN A]]
[[Category: Taylor, A B]]
[[Category: Hart PJ]]
[[Category: Adp-ribosyl transferase]]
[[Category: Taylor AB]]
[[Category: Atypical pneumonia]]
[[Category: Community acquired respiratory distress syndrome]]
[[Category: Mycoplasma pneumoniae]]
[[Category: Toxin]]
[[Category: Transferase]]
[[Category: Virulence]]