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==The crystal structure of Cren7 mutant L28V in complex with dsDNA==
==The crystal structure of Cren7 mutant L28V in complex with dsDNA==
<StructureSection load='5wvy' size='340' side='right' caption='[[5wvy]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='5wvy' size='340' side='right'caption='[[5wvy]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5wvy]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulso Sulso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WVY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WVY FirstGlance]. <br>
<table><tr><td colspan='2'>[[5wvy]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WVY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WVY FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5wvw|5wvw]], [[5wvz|5wvz]], [[5wwc|5wwc]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">creN7, SSO6901 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273057 SULSO])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wvy OCA], [https://pdbe.org/5wvy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wvy RCSB], [https://www.ebi.ac.uk/pdbsum/5wvy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wvy ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wvy OCA], [http://pdbe.org/5wvy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wvy RCSB], [http://www.ebi.ac.uk/pdbsum/5wvy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wvy ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CREN7_SULSO CREN7_SULSO]] A highly abundant probable chromatin protein, it binds double-strand DNA without sequence specificity; there is approximately 1 Cren7 molecule for 12 bp of DNA. Constrains negative DNA supercoils, increases DNA stability against thermal denaturation. Binding does not require protein methylation. Binds single-strand DNA weakly.<ref>PMID:18096617</ref>
[https://www.uniprot.org/uniprot/CREN7_SACS2 CREN7_SACS2] A highly abundant probable chromatin protein, it binds double-strand DNA without sequence specificity; there is approximately 1 Cren7 molecule for 12 bp of DNA. Constrains negative DNA supercoils, increases DNA stability against thermal denaturation. Binding does not require protein methylation. Binds single-strand DNA weakly.<ref>PMID:18096617</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Sulso]]
[[Category: Large Structures]]
[[Category: Chen, Y Y]]
[[Category: Saccharolobus solfataricus P2]]
[[Category: Dong, Y H]]
[[Category: Synthetic construct]]
[[Category: Gong, Y]]
[[Category: Chen YY]]
[[Category: Huang, L]]
[[Category: Dong YH]]
[[Category: Wang, L]]
[[Category: Gong Y]]
[[Category: Zhang, Z F]]
[[Category: Huang L]]
[[Category: Zhao, M H]]
[[Category: Wang L]]
[[Category: Beta-sheet]]
[[Category: Zhang ZF]]
[[Category: Crenarchaeal chromatin protein]]
[[Category: Zhao MH]]
[[Category: Dna binding]]
[[Category: Dna binding protein-dna complex]]
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