5h6y: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

The ~~entry~~ 5h6y is ~~ON HOLD until Nov 15 2018~~

==The BPTF Bromodomain Recognising H4K12Cr peptide==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[5h6y]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5H6Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5H6Y FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCR:N-6-CROTONYL-L-LYSINE'>KCR</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5h6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5h6y OCA], [http://pdbe.org/5h6y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5h6y RCSB], [http://www.ebi.ac.uk/pdbsum/5h6y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5h6y ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/BPTF_HUMAN BPTF_HUMAN]] Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors.

__TOC__

</StructureSection>

[[Category: Hao, Q]]

[[Category: Wang, Y]]

[[Category: Bromodomain]]

[[Category: Crotonylation]]

[[Category: Transcription]]

[[Category: Transcriptional factor]]

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-'''Unreleased structure'''
-The entry 5h6y is ON HOLD  until Nov 15 2018
+==The BPTF Bromodomain Recognising H4K12Cr peptide==
+<StructureSection load='5h6y' size='340' side='right' caption='[[5h6y]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5h6y]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5H6Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5H6Y FirstGlance]. <br>
-Description:
+</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCR:N-6-CROTONYL-L-LYSINE'>KCR</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5h6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5h6y OCA], [http://pdbe.org/5h6y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5h6y RCSB], [http://www.ebi.ac.uk/pdbsum/5h6y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5h6y ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/BPTF_HUMAN BPTF_HUMAN]] Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors.
+__TOC__
+</StructureSection>
+[[Category: Hao, Q]]
+[[Category: Wang, Y]]
+[[Category: Bromodomain]]
+[[Category: Crotonylation]]
+[[Category: Transcription]]
+[[Category: Transcriptional factor]]