2a5r: Difference between revisions

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[[Image:2a5r.gif|left|200px]]
[[Image:2a5r.gif|left|200px]]


{{Structure
<!--
|PDB= 2a5r |SIZE=350|CAPTION= <scene name='initialview01'>2a5r</scene>
The line below this paragraph, containing "STRUCTURE_2a5r", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DI:2&#39;-DEOXYINOSINE-5&#39;-MONOPHOSPHATE'>DI</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=POH:5,10,15,20-TETRA-(4-N-METHYLPYRIDYL)+PORPHINE'>POH</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY=
or leave the SCENE parameter empty for the default display.
|GENE=
-->
|DOMAIN=
{{STRUCTURE_2a5r|  PDB=2a5r |  SCENE= }}  
|RELATEDENTRY=[[1eeg|1EEG]], [[1jjp|1JJP]], [[1y8d|1Y8D]], [[1d6d|1D6D]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a5r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a5r OCA], [http://www.ebi.ac.uk/pdbsum/2a5r PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2a5r RCSB]</span>
}}


'''Complex of tetra-(4-n-methylpyridyl) porphin with monomeric parallel-stranded DNA tetraplex, snap-back 3+1 3' G-tetrad, single-residue chain reversal loops, GAG triad in the context of GAAG diagonal loop, C-MYC promoter, NMR, 6 struct.'''
'''Complex of tetra-(4-n-methylpyridyl) porphin with monomeric parallel-stranded DNA tetraplex, snap-back 3+1 3' G-tetrad, single-residue chain reversal loops, GAG triad in the context of GAAG diagonal loop, C-MYC promoter, NMR, 6 struct.'''
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==About this Structure==
==About this Structure==
2A5R is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A5R OCA].  
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A5R OCA].  


==Reference==
==Reference==
Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter., Phan AT, Kuryavyi V, Gaw HY, Patel DJ, Nat Chem Biol. 2005 Aug;1(3):167-73. Epub 2005 Jul 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16408022 16408022]
Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter., Phan AT, Kuryavyi V, Gaw HY, Patel DJ, Nat Chem Biol. 2005 Aug;1(3):167-73. Epub 2005 Jul 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16408022 16408022]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Gaw, H Y.]]
[[Category: Gaw, H Y.]]
[[Category: Kuryavyi, V V.]]
[[Category: Kuryavyi, V V.]]
[[Category: Patel, D J.]]
[[Category: Patel, D J.]]
[[Category: Phan, A T.]]
[[Category: Phan, A T.]]
[[Category: c-myc promoter 3+1 g-tetrad]]
[[Category: C-myc promoter 3+1 g-tetrad]]
[[Category: gaag loop]]
[[Category: Gaag loop]]
[[Category: gag triad]]
[[Category: Gag triad]]
[[Category: monomeric parallel-stranded quadruplex]]
[[Category: Monomeric parallel-stranded quadruplex]]
[[Category: single nucleotide chain reversal loop]]
[[Category: Single nucleotide chain reversal loop]]
 
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