6bjd: Difference between revisions
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==Crystal Structure of Human Calpain-3 Protease Core in Complex with E-64== | |||
<StructureSection load='6bjd' size='340' side='right' caption='[[6bjd]], [[Resolution|resolution]] 2.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6bjd]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BJD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BJD FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=E64:N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE'>E64</scene>, <scene name='pdbligand=SOR:D-SORBITOL'>SOR</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6bdt|6bdt]]</td></tr> | ||
[[Category: Davies, P | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calpain-3 Calpain-3], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.54 3.4.22.54] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bjd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bjd OCA], [http://pdbe.org/6bjd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bjd RCSB], [http://www.ebi.ac.uk/pdbsum/6bjd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bjd ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[[http://www.uniprot.org/uniprot/CAN3_HUMAN CAN3_HUMAN]] Autosomal recessive limb girdle muscular dystrophy type 2A. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/CAN3_HUMAN CAN3_HUMAN]] Calcium-regulated non-lysosomal thiol-protease. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Calpain-3]] | |||
[[Category: Campbell, R L]] | |||
[[Category: Davies, P L]] | |||
[[Category: Ye, Q]] | [[Category: Ye, Q]] | ||
[[Category: | [[Category: Calcium binding]] | ||
[[Category: Calpain]] | |||
[[Category: Complex]] | |||
[[Category: Cysteine protease]] | |||
[[Category: E-64]] | |||
[[Category: Hydrolase]] | |||
[[Category: P94]] | |||
Revision as of 06:19, 7 February 2018
Crystal Structure of Human Calpain-3 Protease Core in Complex with E-64
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