4log: Difference between revisions
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==The crystal structure of the orphan nuclear receptor PNR ligand binding domain fused with MBP== | ==The crystal structure of the orphan nuclear receptor PNR ligand binding domain fused with MBP== | ||
<StructureSection load='4log' size='340' side='right' caption='[[4log]], [[Resolution|resolution]] 2.70Å' scene=''> | <StructureSection load='4log' size='340' side='right'caption='[[4log]], [[Resolution|resolution]] 2.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4log]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4log]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_O104:H4_str._2009EL-2071 Escherichia coli O104:H4 str. 2009EL-2071] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LOG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LOG FirstGlance]. <br> | ||
</td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4log FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4log OCA], [https://pdbe.org/4log PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4log RCSB], [https://www.ebi.ac.uk/pdbsum/4log PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4log ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Disease == | |||
[https://www.uniprot.org/uniprot/NR2E3_HUMAN NR2E3_HUMAN] Goldmann-Favre syndrome;Retinitis pigmentosa. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.[https://www.uniprot.org/uniprot/NR2E3_HUMAN NR2E3_HUMAN] Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M- and S-cone opsin expression.<ref>PMID:15689355</ref> <ref>PMID:24069298</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 4log" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4log" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Maltose-binding protein 3D structures|Maltose-binding protein 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli O104:H4 str. 2009EL-2071]] | ||
[[Category: Li | [[Category: Homo sapiens]] | ||
[[Category: Li | [[Category: Large Structures]] | ||
[[Category: Melcher | [[Category: Li J]] | ||
[[Category: Soon | [[Category: Li X]] | ||
[[Category: Tan | [[Category: Melcher K]] | ||
[[Category: Xu | [[Category: Soon F-F]] | ||
[[Category: Yong | [[Category: Tan ME]] | ||
[[Category: Zhou | [[Category: Xu HE]] | ||
[[Category: Yong E-L]] | |||
[[Category: Zhou XE]] | |||
