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==Crystal structure of the core catalytic domain of human inositol phosphate multikinase==
==Crystal structure of the core catalytic domain of human inositol phosphate multikinase==
<StructureSection load='5w2g' size='340' side='right' caption='[[5w2g]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='5w2g' size='340' side='right'caption='[[5w2g]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5w2g]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W2G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5W2G FirstGlance]. <br>
<table><tr><td colspan='2'>[[5w2g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W2G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5W2G FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5w2h|5w2h]], [[5w2i|5w2i]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IPMK, IMPK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5w2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w2g OCA], [https://pdbe.org/5w2g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5w2g RCSB], [https://www.ebi.ac.uk/pdbsum/5w2g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5w2g ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5w2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w2g OCA], [http://pdbe.org/5w2g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5w2g RCSB], [http://www.ebi.ac.uk/pdbsum/5w2g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5w2g ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/IPMK_HUMAN IPMK_HUMAN]] Inositol phosphate kinase with a broad substrate specificity. Has a preference for inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) and inositol 1,3,4,6-tetrakisphosphate (Ins(1,3,4,6)P4).<ref>PMID:12027805</ref> <ref>PMID:12223481</ref>
[https://www.uniprot.org/uniprot/IPMK_HUMAN IPMK_HUMAN] Inositol phosphate kinase with a broad substrate specificity. Has a preference for inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) and inositol 1,3,4,6-tetrakisphosphate (Ins(1,3,4,6)P4).<ref>PMID:12027805</ref> <ref>PMID:12223481</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Shears, S B]]
[[Category: Large Structures]]
[[Category: Wang, H]]
[[Category: Shears SB]]
[[Category: Inositol]]
[[Category: Wang H]]
[[Category: Inositol polyphosphate]]
[[Category: Kinase]]
[[Category: Phosphatidylinositol]]
[[Category: Specificity]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/5w2g"