5lug: Difference between revisions
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==Crystal structure of human Spindlin-2B protein in complex with ART(M3L)QTA(2MR)KS peptide== | ==Crystal structure of human Spindlin-2B protein in complex with ART(M3L)QTA(2MR)KS peptide== | ||
<StructureSection load='5lug' size='340' side='right' caption='[[5lug]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='5lug' size='340' side='right'caption='[[5lug]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5lug]] is a 8 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5lug]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LUG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LUG FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2MR:N3,+N4-DIMETHYLARGININE'>2MR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene></td></tr> | ||
< | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lug OCA], [https://pdbe.org/5lug PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lug RCSB], [https://www.ebi.ac.uk/pdbsum/5lug PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lug ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/SPI2B_HUMAN SPI2B_HUMAN] Involved in the regulation of cell cycle progression, this activity is related to the inhibition of apoptosis following the removal of essential growth factors (PubMed:12145692). Exhibits H3K4me3-binding activity (PubMed:29061846).<ref>PMID:12145692</ref> <ref>PMID:29061846</ref> | |||
==See Also== | |||
*[[Spindlin|Spindlin]] | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith | [[Category: Large Structures]] | ||
[[Category: Bountra | [[Category: Arrowsmith CH]] | ||
[[Category: Burgess-Brown | [[Category: Bountra C]] | ||
[[Category: Burgess-Brown N]] | |||
[[Category: Edwards | [[Category: Edwards AM]] | ||
[[Category: Gileadi | [[Category: Gileadi C]] | ||
[[Category: Huber | [[Category: Huber K]] | ||
[[Category: Kopec | [[Category: Kopec J]] | ||
[[Category: Oppermann | [[Category: Oppermann U]] | ||
[[Category: Shrestha | [[Category: Shrestha L]] | ||
[[Category: Srikannathasan | [[Category: Srikannathasan V]] | ||
[[Category: Szykowska | [[Category: Szykowska A]] | ||
[[Category: Talon | [[Category: Talon R]] | ||
[[Category: | [[Category: Von Delft F]] | ||
