5uqc: Difference between revisions
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==Crystal structure of mouse CRMP2== | ==Crystal structure of mouse CRMP2== | ||
<StructureSection load='5uqc' size='340' side='right' caption='[[5uqc]], [[Resolution|resolution]] 1.78Å' scene=''> | <StructureSection load='5uqc' size='340' side='right'caption='[[5uqc]], [[Resolution|resolution]] 1.78Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5uqc]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5uqc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UQC FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.78Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PG:2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL'>1PG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5uqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uqc OCA], [https://pdbe.org/5uqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5uqc RCSB], [https://www.ebi.ac.uk/pdbsum/5uqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5uqc ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/DPYL2_MOUSE DPYL2_MOUSE] Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.<ref>PMID:22057101</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Francois-Moutal | [[Category: Mus musculus]] | ||
[[Category: Khanna | [[Category: Francois-Moutal L]] | ||
[[Category: Khanna | [[Category: Khanna M]] | ||
[[Category: Perez-Miller | [[Category: Khanna R]] | ||
[[Category: Perez-Miller S]] | |||