5vym: Difference between revisions
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==Crystal structure of beta-galactosidase from Bifidobacterium adolescentis== | ==Crystal structure of beta-galactosidase from Bifidobacterium adolescentis== | ||
<StructureSection load='5vym' size='340' side='right' caption='[[5vym]], [[Resolution|resolution]] 2.46Å' scene=''> | <StructureSection load='5vym' size='340' side='right'caption='[[5vym]], [[Resolution|resolution]] 2.46Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5vym]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bifaa Bifaa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VYM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VYM FirstGlance]. <br> | <table><tr><td colspan='2'>[[5vym]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bifaa Bifaa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VYM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VYM FirstGlance]. <br> | ||
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== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/BGAL_BIFAA BGAL_BIFAA]] Involved in the hydrolysis of transgalactooligosaccharides (TOS). Highly active towards Gal(beta1-4)Gal and Gal(beta1-4)-Gal-containing oligosaccharides. Low activity towards Gal(beta1-3)Gal, lactose and Gal(beta1-3)GalOMe. No activity towards Gal(beta1-6)Gal, Gal(beta1-4)Man, Gal(alpha1-4)Gal, Gal(alpha1-3)Gal(beta1-4)Gal, lactulose, 3'fucosyllactose, lacto-N-fucopentaose I, lacto-N-fucopentaose II, cellobiose, maltose or sucrose. No transglycosylation activity is found at high substrate concentrations (100 mg/ml) and only low transglycosylation activity at lower substrate concentrations (10 mg/ml).<ref>PMID:10742215</ref> <ref>PMID:15480628</ref> | [[http://www.uniprot.org/uniprot/BGAL_BIFAA BGAL_BIFAA]] Involved in the hydrolysis of transgalactooligosaccharides (TOS). Highly active towards Gal(beta1-4)Gal and Gal(beta1-4)-Gal-containing oligosaccharides. Low activity towards Gal(beta1-3)Gal, lactose and Gal(beta1-3)GalOMe. No activity towards Gal(beta1-6)Gal, Gal(beta1-4)Man, Gal(alpha1-4)Gal, Gal(alpha1-3)Gal(beta1-4)Gal, lactulose, 3'fucosyllactose, lacto-N-fucopentaose I, lacto-N-fucopentaose II, cellobiose, maltose or sucrose. No transglycosylation activity is found at high substrate concentrations (100 mg/ml) and only low transglycosylation activity at lower substrate concentrations (10 mg/ml).<ref>PMID:10742215</ref> <ref>PMID:15480628</ref> | ||
==See Also== | |||
*[[Galactosidase 3D structures|Galactosidase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Beta-galactosidase]] | [[Category: Beta-galactosidase]] | ||
[[Category: Bifaa]] | [[Category: Bifaa]] | ||
[[Category: Large Structures]] | |||
[[Category: Chang, C]] | [[Category: Chang, C]] | ||
[[Category: Cuff, M]] | [[Category: Cuff, M]] | ||
