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==Crystal structure of DdrB bound to 30b ssDNA==
==Crystal structure of DdrB bound to 30b ssDNA==
<StructureSection load='4noe' size='340' side='right' caption='[[4noe]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='4noe' size='340' side='right'caption='[[4noe]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4noe]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_radiodurans"_raj_et_al._1960 "micrococcus radiodurans" raj et al. 1960]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NOE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NOE FirstGlance]. <br>
<table><tr><td colspan='2'>[[4noe]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NOE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NOE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ddrB, DR0070, DR_0070 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1299 "Micrococcus radiodurans" Raj et al. 1960])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4noe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4noe OCA], [https://pdbe.org/4noe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4noe RCSB], [https://www.ebi.ac.uk/pdbsum/4noe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4noe ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4noe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4noe OCA], [http://pdbe.org/4noe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4noe RCSB], [http://www.ebi.ac.uk/pdbsum/4noe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4noe ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DDRB_DEIRA DDRB_DEIRA]] ssDNA-binding protein that contributes to the ionizing radiation resistance of D.radiodurans. Appears to play a role in DNA repair and genome reconstitution, in a RecA-independent process, and is necessary for recovery from severe genomic fragmentation as a result of exposure to severe levels of ionizing radiation. Binds single-stranded DNA but not duplex DNA.<ref>PMID:15454524</ref> <ref>PMID:19515845</ref>
[https://www.uniprot.org/uniprot/DDRB_DEIRA DDRB_DEIRA] ssDNA-binding protein that contributes to the ionizing radiation resistance of D.radiodurans. Appears to play a role in DNA repair and genome reconstitution, in a RecA-independent process, and is necessary for recovery from severe genomic fragmentation as a result of exposure to severe levels of ionizing radiation. Binds single-stranded DNA but not duplex DNA.<ref>PMID:15454524</ref> <ref>PMID:19515845</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Micrococcus radiodurans raj et al. 1960]]
[[Category: Deinococcus radiodurans]]
[[Category: Junop, M S]]
[[Category: Large Structures]]
[[Category: Sugiman-Marangos, S N]]
[[Category: Junop MS]]
[[Category: Weiss, Y M]]
[[Category: Sugiman-Marangos SN]]
[[Category: Dna binding protein-dna complex]]
[[Category: Weiss YM]]
[[Category: Single-stranded dna annealing]]

Revision as of 08:38, 11 January 2023

Crystal structure of DdrB bound to 30b ssDNA

4noe, resolution 2.20Å

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