5yr7: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5yr7 is ~~ON HOLD until Paper Publication~~

==Human methionine aminopeptidase type 1b (F309L mutant)==

~~Authors~~: ~~Pillalamarri~~, V., ~~Arya~~, T., ~~Addlagatta~~, A.

== Structural highlights ==

<table><tr><td colspan='2'>[[5yr7]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YR7 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YR7 FirstGlance].

~~Description~~: ~~Human~~ methionine ~~aminopeptidase type 1b~~ (~~F309L mutant~~)

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Methionyl_aminopeptidase Methionyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.18 3.4.11.18] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yr7 OCA], [http://pdbe.org/5yr7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yr7 RCSB], [http://www.ebi.ac.uk/pdbsum/5yr7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yr7 ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/MAP11_HUMAN MAP11_HUMAN]] Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Required for normal progression through the cell cycle.[HAMAP-Rule:MF_03174]<ref>PMID:16274222</ref> <ref>PMID:17114291</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Methionyl aminopeptidase]]

[[Category: Addlagatta, A]]

[[Category: Arya, T]]

[[Category: Pillalamarri, V]]

[[Category: ~~Arya, T~~]]

[[Category: Hydrolase]]

[[Category: Metal binding protein]]

[[Category: Methionine aminopeptidase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5yr7 is ON HOLD  until Paper Publication
+==Human methionine aminopeptidase type 1b (F309L mutant)==
+<StructureSection load='5yr7' size='340' side='right' caption='[[5yr7]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
-Authors: Pillalamarri, V., Arya, T., Addlagatta, A.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5yr7]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YR7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YR7 FirstGlance]. <br>
-Description: Human methionine aminopeptidase type 1b (F309L mutant)
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionyl_aminopeptidase Methionyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.18 3.4.11.18] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yr7 OCA], [http://pdbe.org/5yr7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yr7 RCSB], [http://www.ebi.ac.uk/pdbsum/5yr7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yr7 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/MAP11_HUMAN MAP11_HUMAN]] Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Required for normal progression through the cell cycle.[HAMAP-Rule:MF_03174]<ref>PMID:16274222</ref> <ref>PMID:17114291</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Methionyl aminopeptidase]]
 [[Category: Addlagatta, A]]
+[[Category: Arya, T]]
 [[Category: Pillalamarri, V]]
-[[Category: Arya, T]]
+[[Category: Hydrolase]]
+[[Category: Metal binding protein]]
+[[Category: Methionine aminopeptidase]]