6ewk: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6ewk is ~~ON HOLD until Paper Publication~~

==T. californica AChE in complex with a 3-hydroxy-2-pyridine aldoxime.==

~~Authors~~: ~~de la Mora~~, E., ~~Weik~~, M., ~~Braiki~~, A., ~~Mougeot, R~~.~~, Jean, L~~., ~~Renard, P~~.I.

== Structural highlights ==

<table><tr><td colspan='2'>[[6ewk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Tetronarce_californica Tetronarce californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EWK OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EWK FirstGlance].

~~Description~~: T. ~~californica AChE~~ in ~~complex with a 3~~-~~hydroxy-2-pyridine aldoxime~~.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=RM0:2-[(~{E})-hydroxyiminomethyl]-6-(5-morpholin-4-ylpentyl)pyridin-3-ol'>RM0</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </td></tr>

[[Category: ~~Renard~~, ~~P.I~~]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ewk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ewk OCA], [http://pdbe.org/6ewk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ewk RCSB], [http://www.ebi.ac.uk/pdbsum/6ewk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ewk ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/ACES_TETCF ACES_TETCF]] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions.

__TOC__

</StructureSection>

[[Category: Acetylcholinesterase]]

[[Category: Tetronarce californica]]

[[Category: Braiki, A]]

[[Category: Jean, L]]

[[Category: Mora, E de la]]

[[Category: Mougeot, R]]

[[Category: ~~Jean~~, ~~L]]~~

[[Category: Renard, P I]]

~~[[Category: Braiki, A]]~~

~~[[Category: De La Mora, E~~]]

[[Category: Weik, M]]

[[Category: Aldehyde oxime]]

[[Category: Hydrolase]]

[[Category: Organophosphate poisoning]]

[[Category: Reactivator]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6ewk is ON HOLD  until Paper Publication
+==T. californica AChE in complex with a 3-hydroxy-2-pyridine aldoxime.==
+<StructureSection load='6ewk' size='340' side='right' caption='[[6ewk]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
-Authors: de la Mora, E., Weik, M., Braiki, A., Mougeot, R., Jean, L., Renard, P.I.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6ewk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Tetronarce_californica Tetronarce californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EWK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EWK FirstGlance]. <br>
-Description: T. californica AChE in complex with a 3-hydroxy-2-pyridine aldoxime.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=RM0:2-[(~{E})-hydroxyiminomethyl]-6-(5-morpholin-4-ylpentyl)pyridin-3-ol'>RM0</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr>
-[[Category: Renard, P.I]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ewk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ewk OCA], [http://pdbe.org/6ewk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ewk RCSB], [http://www.ebi.ac.uk/pdbsum/6ewk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ewk ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/ACES_TETCF ACES_TETCF]] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions.
+__TOC__
+</StructureSection>
+[[Category: Acetylcholinesterase]]
+[[Category: Tetronarce californica]]
+[[Category: Braiki, A]]
+[[Category: Jean, L]]
+[[Category: Mora, E de la]]
 [[Category: Mougeot, R]]
-[[Category: Jean, L]]
+[[Category: Renard, P I]]
-[[Category: Braiki, A]]
-[[Category: De La Mora, E]]
 [[Category: Weik, M]]
+[[Category: Aldehyde oxime]]
+[[Category: Hydrolase]]
+[[Category: Organophosphate poisoning]]
+[[Category: Reactivator]]