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==Crystal structure of the Bateman domain of murine magnesium transporter CNNM2 bound to AMP==
==Crystal structure of the Bateman domain of murine magnesium transporter CNNM2 bound to AMP==
<StructureSection load='4p1g' size='340' side='right' caption='[[4p1g]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='4p1g' size='340' side='right'caption='[[4p1g]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4p1g]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P1G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P1G FirstGlance]. <br>
<table><tr><td colspan='2'>[[4p1g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P1G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4P1G FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cnnm2, Acdp2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4p1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p1g OCA], [https://pdbe.org/4p1g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4p1g RCSB], [https://www.ebi.ac.uk/pdbsum/4p1g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4p1g ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p1g OCA], [http://pdbe.org/4p1g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4p1g RCSB], [http://www.ebi.ac.uk/pdbsum/4p1g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4p1g ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CNNM2_MOUSE CNNM2_MOUSE]] Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+).<ref>PMID:15899945</ref>
[https://www.uniprot.org/uniprot/CNNM2_MOUSE CNNM2_MOUSE] Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+).<ref>PMID:15899945</ref>  
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lk3 transgenic mice]]
[[Category: Large Structures]]
[[Category: Abascal-Palacios, G]]
[[Category: Mus musculus]]
[[Category: Accardi, A]]
[[Category: Abascal-Palacios G]]
[[Category: Corral-Rodriguez, M A]]
[[Category: Accardi A]]
[[Category: Diercks, T]]
[[Category: Corral-Rodriguez MA]]
[[Category: Encinar, J A]]
[[Category: Diercks T]]
[[Category: Ereno-Orbea, J]]
[[Category: Encinar JA]]
[[Category: Martinez-Cruz, L A]]
[[Category: Ereno-Orbea J]]
[[Category: Muller, D]]
[[Category: Martinez-Cruz LA]]
[[Category: Oyenarte, I]]
[[Category: Muller D]]
[[Category: Spiwok, V]]
[[Category: Oyenarte I]]
[[Category: Stuiver, M]]
[[Category: Spiwok V]]
[[Category: Terashima, H]]
[[Category: Stuiver M]]
[[Category: Acdp]]
[[Category: Terashima H]]
[[Category: Cyclin m]]
[[Category: Hypomagnesemia]]
[[Category: Magnesium homeostasis]]
[[Category: Rare disease]]
[[Category: Transport]]
[[Category: Transport protein]]

Revision as of 12:36, 1 February 2023

Crystal structure of the Bateman domain of murine magnesium transporter CNNM2 bound to AMP

4p1g, resolution 2.60Å

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