4qpk: Difference between revisions
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==1.7 Angstrom Structure of a Bacterial Phosphotransferase== | ==1.7 Angstrom Structure of a Bacterial Phosphotransferase== | ||
<StructureSection load='4qpk' size='340' side='right' caption='[[4qpk]], [[Resolution|resolution]] 1.66Å' scene=''> | <StructureSection load='4qpk' size='340' side='right'caption='[[4qpk]], [[Resolution|resolution]] 1.66Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4qpk]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4qpk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Brucella_abortus_2308 Brucella abortus 2308]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QPK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QPK FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qpk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qpk OCA], [https://pdbe.org/4qpk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qpk RCSB], [https://www.ebi.ac.uk/pdbsum/4qpk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qpk ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/CHPT_BRUA2 CHPT_BRUA2] Component of a regulatory phosphorelay system that controls B.abortus cell growth, division, and intracellular survival inside mammalian host cells. This signaling pathway is composed of CckA, ChpT, CtrA and CpdR. ChpT efficiently and specifically shuttles phosphoryl groups from the CckA kinase to the receiver domains of both CtrA and CpdR. Does not bind ATP. Overexpression of chpT results in a defect in cell morphology, DNA content, and intracellular survival in human macrophages.<ref>PMID:26124143</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
*[[Phosphotransferase|Phosphotransferase]] | *[[Phosphotransferase 3D structures|Phosphotransferase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Brucella abortus 2308]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Crosson S]] | ||
[[Category: | [[Category: Herrou J]] | ||
[[Category: | [[Category: Willett JW]] | ||
