4qpj: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
Line 1: Line 1:


==2.7 Angstrom Structure of a Phosphotransferase in Complex with a Receiver Domain==
==2.7 Angstrom Structure of a Phosphotransferase in Complex with a Receiver Domain==
<StructureSection load='4qpj' size='340' side='right' caption='[[4qpj]], [[Resolution|resolution]] 2.74&Aring;' scene=''>
<StructureSection load='4qpj' size='340' side='right'caption='[[4qpj]], [[Resolution|resolution]] 2.74&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4qpj]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Brua2 Brua2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QPJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QPJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[4qpj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Brucella_abortus_2308 Brucella abortus 2308]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QPJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QPJ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4qpk|4qpk]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qpj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qpj OCA], [https://pdbe.org/4qpj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qpj RCSB], [https://www.ebi.ac.uk/pdbsum/4qpj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qpj ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAB1_1613, BruAb1_1585 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=359391 BRUA2]), BAB1_1614, BruAb1_1586, ctrA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=359391 BRUA2])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qpj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qpj OCA], [http://pdbe.org/4qpj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qpj RCSB], [http://www.ebi.ac.uk/pdbsum/4qpj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qpj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CTRA_BRUA2 CTRA_BRUA2]] Essential protein that plays a role in the control of cell division, possibly through the transcriptional regulation of ccrM, rpoD, pleC, minC and ftsZ genes.  
[https://www.uniprot.org/uniprot/CHPT_BRUA2 CHPT_BRUA2] Component of a regulatory phosphorelay system that controls B.abortus cell growth, division, and intracellular survival inside mammalian host cells. This signaling pathway is composed of CckA, ChpT, CtrA and CpdR. ChpT efficiently and specifically shuttles phosphoryl groups from the CckA kinase to the receiver domains of both CtrA and CpdR. Does not bind ATP. Overexpression of chpT results in a defect in cell morphology, DNA content, and intracellular survival in human macrophages.<ref>PMID:26124143</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 22: Line 20:


==See Also==
==See Also==
*[[Phosphotransferase|Phosphotransferase]]
*[[Phosphotransferase 3D structures|Phosphotransferase 3D structures]]
*[[Response regulator 3D structure|Response regulator 3D structure]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Brua2]]
[[Category: Brucella abortus 2308]]
[[Category: Crosson, S]]
[[Category: Large Structures]]
[[Category: Herrou, J]]
[[Category: Crosson S]]
[[Category: Willett, J W]]
[[Category: Herrou J]]
[[Category: Atp-binding]]
[[Category: Willett JW]]
[[Category: Catalytic domain]]
[[Category: Chpt]]
[[Category: Chpt-ctra complex]]
[[Category: Ctra]]
[[Category: Histidine kinase]]
[[Category: Histidine kinase like]]
[[Category: Hpt]]
[[Category: Phosphotransferase]]
[[Category: Response regulator]]
[[Category: Rr]]
[[Category: Signaling protein-dna binding protein complex]]
Retrieved from "https://proteopedia.org/4qpj"