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==Crystal structure of the ornithine aminotransferase from Toxoplasma gondii ME49 in a complex with the Schiff base between PLP and Lys286==
==Crystal structure of the ornithine aminotransferase from Toxoplasma gondii ME49 in a complex with the Schiff base between PLP and Lys286==
<StructureSection load='4zlv' size='340' side='right' caption='[[4zlv]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='4zlv' size='340' side='right'caption='[[4zlv]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4zlv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxgm Toxgm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZLV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZLV FirstGlance]. <br>
<table><tr><td colspan='2'>[[4zlv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Toxoplasma_gondii_ME49 Toxoplasma gondii ME49]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZLV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZLV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TGME49_269110 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=508771 TOXGM])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zlv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zlv OCA], [https://pdbe.org/4zlv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zlv RCSB], [https://www.ebi.ac.uk/pdbsum/4zlv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zlv ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ornithine_aminotransferase Ornithine aminotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.13 2.6.1.13] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zlv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zlv OCA], [http://pdbe.org/4zlv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zlv RCSB], [http://www.ebi.ac.uk/pdbsum/4zlv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zlv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/S8EY38_TOXGM S8EY38_TOXGM]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ornithine aminotransferase]]
[[Category: Large Structures]]
[[Category: Toxgm]]
[[Category: Toxoplasma gondii ME49]]
[[Category: Anderson, W F]]
[[Category: Anderson WF]]
[[Category: Structural genomic]]
[[Category: Filippova EV]]
[[Category: Filippova, E V]]
[[Category: Flores K]]
[[Category: Flores, K]]
[[Category: McLeod R]]
[[Category: Le, H Van]]
[[Category: Minasov G]]
[[Category: McLeod, R]]
[[Category: Silverman RB]]
[[Category: Minasov, G]]
[[Category: Van Le H]]
[[Category: Silverman, R B]]
[[Category: Csgid]]
[[Category: Transferase]]

Revision as of 07:32, 18 May 2023

Crystal structure of the ornithine aminotransferase from Toxoplasma gondii ME49 in a complex with the Schiff base between PLP and Lys286

4zlv, resolution 1.80Å

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