5v7c: Difference between revisions

<StructureSection load='5v7c' size='340' side='right'caption='[[5v7c]], [[Resolution|resolution]] 2.59&Aring;' scene=''>

<table><tr><td colspan='2'>[[5v7c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V7C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5V7C FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.59&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5v7c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v7c OCA], [https://pdbe.org/5v7c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5v7c RCSB], [https://www.ebi.ac.uk/pdbsum/5v7c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5v7c ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/LARP1_HUMAN LARP1_HUMAN] RNA-binding protein that promotes translation of specific classes of mRNAs downstream of the mTORC1 complex. Associates with the mRNA 5'cap in an MTOR-dependent manner and associates with mRNAs containing a 5' terminal oligopyrimidine (5'TOP) motif, which is present in mRNAs encoding for ribosomal proteins and several components of the translation machinery. Associates with actively translating ribosomes via interaction with PABPC1/PABP and stimulates translation of mRNAs containing a 5'TOP, thereby regulating cell growth and proliferation.<ref>PMID:20430826</ref> <ref>PMID:23711370</ref> <ref>PMID:24532714</ref>  

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Al-Ashtal HA]]

[[Category: Berman AJ]]

[[Category: Lahr RM]]