2bpa: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:2bpa.gif|left|200px]] | [[Image:2bpa.gif|left|200px]] | ||
<!-- | |||
The line below this paragraph, containing "STRUCTURE_2bpa", creates the "Structure Box" on the page. | |||
You may change the PDB parameter (which sets the PDB file loaded into the applet) | |||
or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | |||
| | or leave the SCENE parameter empty for the default display. | ||
| | --> | ||
{{STRUCTURE_2bpa| PDB=2bpa | SCENE= }} | |||
}} | |||
'''ATOMIC STRUCTURE OF SINGLE-STRANDED DNA BACTERIOPHAGE PHIX174 AND ITS FUNCTIONAL IMPLICATIONS''' | '''ATOMIC STRUCTURE OF SINGLE-STRANDED DNA BACTERIOPHAGE PHIX174 AND ITS FUNCTIONAL IMPLICATIONS''' | ||
| Line 34: | Line 31: | ||
[[Category: Willingmann, P.]] | [[Category: Willingmann, P.]] | ||
[[Category: Xia, D.]] | [[Category: Xia, D.]] | ||
[[Category: | [[Category: Icosahedral virus]] | ||
[[Category: | [[Category: Protein-dna complex]] | ||
[[Category: | [[Category: Single strand]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 20:36:25 2008'' | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | |||
Revision as of 17:36, 3 May 2008
ATOMIC STRUCTURE OF SINGLE-STRANDED DNA BACTERIOPHAGE PHIX174 AND ITS FUNCTIONAL IMPLICATIONS
Overview
The mechanism of DNA ejection, viral assembly and evolution are related to the structure of bacteriophage phi X174. The F protein forms a T = 1 capsid whose major folding motif is the eight-stranded antiparallel beta barrel found in many other icosahedral viruses. Groups of 5 G proteins form 12 dominating spikes that enclose a hydrophilic channel containing some diffuse electron density. Each G protein is a tight beta barrel with its strands running radially outwards and with a topology similar to that of the F protein. The 12 'pilot' H proteins per virion may be partially located in the putative ion channel. The small, basic J protein is associated with the DNA and is situated in an interior cleft of the F protein. Tentatively, there are three regions of partially ordered DNA structure,
About this Structure
2BPA is a Protein complex structure of sequences from Enterobacteria phage phix174. Full crystallographic information is available from OCA.
Reference
Atomic structure of single-stranded DNA bacteriophage phi X174 and its functional implications., McKenna R, Xia D, Willingmann P, Ilag LL, Krishnaswamy S, Rossmann MG, Olson NH, Baker TS, Incardona NL, Nature. 1992 Jan 9;355(6356):137-43. PMID:1370343 Page seeded by OCA on Sat May 3 20:36:25 2008
