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==Crystal structure of red abalone VERL repeat 1 with linker at 2.0 A resolution==
==Crystal structure of red abalone VERL repeat 1 with linker at 2.0 A resolution==
<StructureSection load='5ii4' size='340' side='right' caption='[[5ii4]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='5ii4' size='340' side='right'caption='[[5ii4]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ii4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/California_red_abalone California red abalone]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5II4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5II4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ii4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_O157:H7 Escherichia coli O157:H7] and [https://en.wikipedia.org/wiki/Haliotis_rufescens Haliotis rufescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5II4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5II4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MAL:MALTOSE'>MAL</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ii5|5ii5]], [[5iic|5iic]], [[3d4c|3d4c]], [[3d4g|3d4g]], [[3ef7|3ef7]], [[3nk3|3nk3]], [[3nk4|3nk4]], [[5ii6|5ii6]], [[5iia|5iia]], [[5iib|5iib]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PRD_900001:alpha-maltose'>PRD_900001</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VERL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6454 California red abalone]), malE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6454 California red abalone])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ii4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ii4 OCA], [https://pdbe.org/5ii4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ii4 RCSB], [https://www.ebi.ac.uk/pdbsum/5ii4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ii4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ii4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ii4 OCA], [http://pdbe.org/5ii4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ii4 RCSB], [http://www.ebi.ac.uk/pdbsum/5ii4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ii4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MALE_ECO57 MALE_ECO57]] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides (By similarity).  
[https://www.uniprot.org/uniprot/VERL_HALRU VERL_HALRU] Structural component of the egg vitelline envelope; forms long filaments. Functions as species-specific receptor for the sperm protein lysin; prevents fertilization by sperm from other species. Each VERL chain can bind multiple copies of the sperm protein lysin; this creates a 3 um hole in the egg vitelline envelope through which the sperm passes.<ref>PMID:28622512</ref> <ref>PMID:9192632</ref> [https://www.uniprot.org/uniprot/MALE_ECO57 MALE_ECO57] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: California red abalone]]
[[Category: Escherichia coli O157:H7]]
[[Category: Al-Hosseini, H Sadat]]
[[Category: Haliotis rufescens]]
[[Category: Jovine, L]]
[[Category: Large Structures]]
[[Category: Nishimura, K]]
[[Category: Jovine L]]
[[Category: Raj, I]]
[[Category: Nishimura K]]
[[Category: Cell adhesion]]
[[Category: Raj I]]
[[Category: Egg-sperm interaction]]
[[Category: Sadat Al-Hosseini H]]
[[Category: Fertilization]]
[[Category: Gamete recognition]]
[[Category: Sperm receptor]]
[[Category: Vitelline envelope]]
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