Unusual sequence numbering: Difference between revisions

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Eric Martz (talk | contribs)
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===Gap Due To Missing Residues===
===Gap Due To Missing Residues===
It is not uncommon for a surface loop of the crystallized protein to be disordered. Often such loops are [[intrinsically disordered]]. The disorder blurs the electron density map for that loop, and the loop residues are not given coordinates in the model: they are missing in the model. However, they were not missing in the crystallized protein.  
It is not uncommon for a surface loop of the crystallized protein to be disordered. Often such loops are [[Intrinsically Disordered Protein|intrinsically disordered]]. The disorder blurs the electron density map for that loop, and the loop residues are not given coordinates in the model: they are missing in the model. However, they were not missing in the crystallized protein. This causes a gap in the sequence numbers in the PDB file. An example is


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