6bgp: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6bgp is ~~ON HOLD until Paper Publication~~

==Crystal Structure of Human Calpain-3 Protease Core Mutant-C129A==

~~Authors~~: Ye, Q., ~~Campbell~~, R.L., ~~Davies~~, P.L.

== Structural highlights ==

<table><tr><td colspan='2'>[[6bgp]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BGP OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BGP FirstGlance].

~~Description~~: ~~Crystal Structure of Human~~ Calpain-3 ~~Protease Core Mutant-C129A~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[6bdt|6bdt]]</td></tr>

[[Category: Davies, P.L]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Calpain-3 Calpain-3], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.54 3.4.22.54] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bgp OCA], [http://pdbe.org/6bgp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bgp RCSB], [http://www.ebi.ac.uk/pdbsum/6bgp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bgp ProSAT]</td></tr>

</table>

== Disease ==

[[http://www.uniprot.org/uniprot/CAN3_HUMAN CAN3_HUMAN]] Autosomal recessive limb girdle muscular dystrophy type 2A. The disease is caused by mutations affecting the gene represented in this entry.

== Function ==

[[http://www.uniprot.org/uniprot/CAN3_HUMAN CAN3_HUMAN]] Calcium-regulated non-lysosomal thiol-protease.

__TOC__

</StructureSection>

[[Category: Calpain-3]]

[[Category: Campbell, R L]]

[[Category: Davies, P L]]

[[Category: Ye, Q]]

[[Category: ~~Campbell, R.L~~]]

[[Category: Calcium binding]]

[[Category: Calpain]]

[[Category: Cysteine protease]]

[[Category: Hydrolase]]

[[Category: P94]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6bgp is ON HOLD  until Paper Publication
+==Crystal Structure of Human Calpain-3 Protease Core Mutant-C129A==
+<StructureSection load='6bgp' size='340' side='right' caption='[[6bgp]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
-Authors: Ye, Q., Campbell, R.L., Davies, P.L.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6bgp]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BGP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BGP FirstGlance]. <br>
-Description: Crystal Structure of Human Calpain-3 Protease Core Mutant-C129A
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6bdt|6bdt]]</td></tr>
-[[Category: Davies, P.L]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calpain-3 Calpain-3], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.54 3.4.22.54] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bgp OCA], [http://pdbe.org/6bgp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bgp RCSB], [http://www.ebi.ac.uk/pdbsum/6bgp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bgp ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[[http://www.uniprot.org/uniprot/CAN3_HUMAN CAN3_HUMAN]] Autosomal recessive limb girdle muscular dystrophy type 2A. The disease is caused by mutations affecting the gene represented in this entry.
+== Function ==
+[[http://www.uniprot.org/uniprot/CAN3_HUMAN CAN3_HUMAN]] Calcium-regulated non-lysosomal thiol-protease.
+__TOC__
+</StructureSection>
+[[Category: Calpain-3]]
+[[Category: Campbell, R L]]
+[[Category: Davies, P L]]
 [[Category: Ye, Q]]
-[[Category: Campbell, R.L]]
+[[Category: Calcium binding]]
+[[Category: Calpain]]
+[[Category: Cysteine protease]]
+[[Category: Hydrolase]]
+[[Category: P94]]