6bq1: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

The entry ~~6bq1 is ON HOLD~~

==Human PI4KIIIa lipid kinase complex==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6bq1]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BQ1 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BQ1 FirstGlance].

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=E4S:5-{2-amino-1-[4-(morpholin-4-yl)phenyl]-1H-benzimidazol-6-yl}-N-(2-fluorophenyl)-2-methoxypyridine-3-sulfonamide'>E4S</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='NonStdRes'><td class="sblockLbl">[[Non-Standard_Residue|NonStd Res:]]</td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/1-phosphatidylinositol_4-kinase 1-phosphatidylinositol 4-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.67 2.7.1.67] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bq1 OCA], [http://pdbe.org/6bq1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bq1 RCSB], [http://www.ebi.ac.uk/pdbsum/6bq1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bq1 ProSAT]</td></tr>

</table>

== Disease ==

[[http://www.uniprot.org/uniprot/HYCCI_HUMAN HYCCI_HUMAN]] Hypomyelination - congenital cataract. The disease is caused by mutations affecting the gene represented in this entry.

== Function ==

[[http://www.uniprot.org/uniprot/HYCCI_HUMAN HYCCI_HUMAN]] May have a role in the beta-catenin/Lef signaling pathway. May have a role in the process of myelination of the central and peripheral nervous system.<ref>PMID:16951682</ref>

== References ==

__TOC__

</StructureSection>

[[Category: 1-phosphatidylinositol 4-kinase]]

[[Category: Baskin, J]]

[[Category: Camilli, P D]]

[[Category: Dobbs, K]]

[[Category: Lees, J A]]

[[Category: Notarangelo, L D]]

[[Category: Oh, M]]

[[Category: Reinisch, K M]]

[[Category: Schauder, C M]]

[[Category: Walz, T]]

[[Category: Yu, X]]

[[Category: Zhang, Y]]

[[Category: Kinase]]

[[Category: Phosphoinositide synthesis]]

[[Category: Transferase-signaling protein complex]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6bq1 is ON HOLD
+==Human PI4KIIIa lipid kinase complex==
+<StructureSection load='6bq1' size='340' side='right' caption='[[6bq1]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6bq1]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BQ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BQ1 FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=E4S:5-{2-amino-1-[4-(morpholin-4-yl)phenyl]-1H-benzimidazol-6-yl}-N-(2-fluorophenyl)-2-methoxypyridine-3-sulfonamide'>E4S</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/1-phosphatidylinositol_4-kinase 1-phosphatidylinositol 4-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.67 2.7.1.67] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bq1 OCA], [http://pdbe.org/6bq1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bq1 RCSB], [http://www.ebi.ac.uk/pdbsum/6bq1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bq1 ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[[http://www.uniprot.org/uniprot/HYCCI_HUMAN HYCCI_HUMAN]] Hypomyelination - congenital cataract. The disease is caused by mutations affecting the gene represented in this entry.
+== Function ==
+[[http://www.uniprot.org/uniprot/HYCCI_HUMAN HYCCI_HUMAN]] May have a role in the beta-catenin/Lef signaling pathway. May have a role in the process of myelination of the central and peripheral nervous system.<ref>PMID:16951682</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: 1-phosphatidylinositol 4-kinase]]
+[[Category: Baskin, J]]
+[[Category: Camilli, P D]]
+[[Category: Dobbs, K]]
+[[Category: Lees, J A]]
+[[Category: Notarangelo, L D]]
+[[Category: Oh, M]]
+[[Category: Reinisch, K M]]
+[[Category: Schauder, C M]]
+[[Category: Walz, T]]
+[[Category: Yu, X]]
+[[Category: Zhang, Y]]
+[[Category: Kinase]]
+[[Category: Phosphoinositide synthesis]]
+[[Category: Transferase-signaling protein complex]]