6bsz: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6bsz is ~~ON HOLD~~

==Human mGlu8 Receptor complexed with glutamate==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6bsz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BSZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BSZ FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GGL:GAMMA-L-GLUTAMIC+ACID'>GGL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bsz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bsz OCA], [http://pdbe.org/6bsz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bsz RCSB], [http://www.ebi.ac.uk/pdbsum/6bsz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bsz ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/GRM8_HUMAN GRM8_HUMAN]] G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.<ref>PMID:9473604</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Atwell, S]]

[[Category: Chen, Q]]

[[Category: Hao, J]]

[[Category: Ho, J D]]

[[Category: Monn, J A]]

[[Category: Schkeryantz, J M]]

[[Category: Vargas, M C]]

[[Category: Wang, J]]

[[Category: Zhang, A]]

[[Category: Gene id: 2918]]

[[Category: Glutamate]]

[[Category: Grm8]]

[[Category: Mglur8]]

[[Category: Signaling protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6bsz is ON HOLD
+==Human mGlu8 Receptor complexed with glutamate==
+<StructureSection load='6bsz' size='340' side='right' caption='[[6bsz]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6bsz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BSZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BSZ FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GGL:GAMMA-L-GLUTAMIC+ACID'>GGL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bsz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bsz OCA], [http://pdbe.org/6bsz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bsz RCSB], [http://www.ebi.ac.uk/pdbsum/6bsz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bsz ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/GRM8_HUMAN GRM8_HUMAN]] G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.<ref>PMID:9473604</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Atwell, S]]
+[[Category: Chen, Q]]
+[[Category: Hao, J]]
+[[Category: Ho, J D]]
+[[Category: Monn, J A]]
+[[Category: Schkeryantz, J M]]
+[[Category: Vargas, M C]]
+[[Category: Wang, J]]
+[[Category: Zhang, A]]
+[[Category: Gene id: 2918]]
+[[Category: Glutamate]]
+[[Category: Grm8]]
+[[Category: Mglur8]]
+[[Category: Signaling protein]]