6f5f: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6f5f is ~~ON HOLD~~

==Structure of ARTD2/PARP2 WGR domain bound to double strand DNA with 5 nucleotide overhang and 5'phosphate==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6f5f]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F5F OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F5F FirstGlance].

~~Description~~:

</td></tr><tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] </td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f5f OCA], [http://pdbe.org/6f5f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f5f RCSB], [http://www.ebi.ac.uk/pdbsum/6f5f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f5f ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/PARP2_HUMAN PARP2_HUMAN]] Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.

__TOC__

</StructureSection>

[[Category: Haikarainen, T]]

[[Category: Lehtio, L]]

[[Category: Obaji, E]]

[[Category: Adp-ribosylation]]

[[Category: Artd2]]

[[Category: Dna binding protein]]

[[Category: Dna end joining]]

[[Category: Dna repair]]

[[Category: Non-phosphorylated dna]]

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-'''Unreleased structure'''
-The entry 6f5f is ON HOLD
+==Structure of ARTD2/PARP2 WGR domain bound to double strand DNA with 5 nucleotide overhang and 5'phosphate==
+<StructureSection load='6f5f' size='340' side='right' caption='[[6f5f]], [[Resolution|resolution]] 2.98&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6f5f]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F5F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F5F FirstGlance]. <br>
-Description:
+</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] </span></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f5f OCA], [http://pdbe.org/6f5f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f5f RCSB], [http://www.ebi.ac.uk/pdbsum/6f5f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f5f ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/PARP2_HUMAN PARP2_HUMAN]] Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
+__TOC__
+</StructureSection>
+[[Category: Haikarainen, T]]
+[[Category: Lehtio, L]]
+[[Category: Obaji, E]]
+[[Category: Adp-ribosylation]]
+[[Category: Artd2]]
+[[Category: Dna binding protein]]
+[[Category: Dna end joining]]
+[[Category: Dna repair]]
+[[Category: Non-phosphorylated dna]]