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==Methylation at position 32 of tRNA catalyzed by TrmJ alters oxidative stress response in Pseudomonas aeruiginosa==
==Methylation at position 32 of tRNA catalyzed by TrmJ alters oxidative stress response in Pseudomonas aeruiginosa==
<StructureSection load='5gm8' size='340' side='right' caption='[[5gm8]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='5gm8' size='340' side='right'caption='[[5gm8]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5gm8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GM8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GM8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5gm8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GM8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SFG:SINEFUNGIN'>SFG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5gmb|5gmb]], [[5gmc|5gmc]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SFG:SINEFUNGIN'>SFG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trmJ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5gm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gm8 OCA], [https://pdbe.org/5gm8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5gm8 RCSB], [https://www.ebi.ac.uk/pdbsum/5gm8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5gm8 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(cytidine(32)/uridine(32)-2'-O)-methyltransferase tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.200 2.1.1.200] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gm8 OCA], [http://pdbe.org/5gm8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gm8 RCSB], [http://www.ebi.ac.uk/pdbsum/5gm8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gm8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/A0A072ZPM2_PSEAI A0A072ZPM2_PSEAI]] Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.[RuleBase:RU362024]  
[https://www.uniprot.org/uniprot/A0A072ZPM2_PSEAI A0A072ZPM2_PSEAI] Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.[RuleBase:RU362024]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5gm8" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5gm8" style="background-color:#fffaf0;"></div>
==See Also==
*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atichartpongkul, S]]
[[Category: Large Structures]]
[[Category: Chionh, Y H]]
[[Category: DeMott, M S]]
[[Category: Dedon, P C]]
[[Category: Fuangthong, M]]
[[Category: Jaroensuk, J]]
[[Category: Lescar, J]]
[[Category: Liew, C W]]
[[Category: McBee, M E]]
[[Category: Mongkolsuk, S]]
[[Category: Prestwich, E G]]
[[Category: Thongdee, N]]
[[Category: Wong, Y H]]
[[Category: Oxidative stress]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Transferase]]
[[Category: Atichartpongkul S]]
[[Category: Trmj]]
[[Category: Chionh YH]]
[[Category: Trna methyltransferase]]
[[Category: DeMott MS]]
[[Category: Trna modification]]
[[Category: Dedon PC]]
[[Category: Wobble base]]
[[Category: Fuangthong M]]
[[Category: Jaroensuk J]]
[[Category: Lescar J]]
[[Category: Liew CW]]
[[Category: McBee ME]]
[[Category: Mongkolsuk S]]
[[Category: Prestwich EG]]
[[Category: Thongdee N]]
[[Category: Wong YH]]

Latest revision as of 11:35, 2 August 2023

Methylation at position 32 of tRNA catalyzed by TrmJ alters oxidative stress response in Pseudomonas aeruiginosa

5gm8, resolution 2.20Å

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