6fax: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6fax is ~~ON HOLD~~ ~~until Paper Publication~~

==Complex of Human CD40 Ectodomain with Lob 7.4 Fab==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6fax]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FAX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FAX FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fax OCA], [http://pdbe.org/6fax PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fax RCSB], [http://www.ebi.ac.uk/pdbsum/6fax PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fax ProSAT]</span></td></tr>

[[Category: ~~Unreleased Structures~~]]

</table>

== Disease ==

[[http://www.uniprot.org/uniprot/TNR5_HUMAN TNR5_HUMAN]] Defects in CD40 are the cause of immunodeficiency with hyper-IgM type 3 (HIGM3) [MIM:[http://omim.org/entry/606843 606843]]. A rare immunodeficiency syndrome characterized by normal or elevated serum IgM levels with absence of IgG, IgA, and IgE. It results in a profound susceptibility to bacterial infections.<ref>PMID:11675497</ref>

== Function ==

[[http://www.uniprot.org/uniprot/TNR5_HUMAN TNR5_HUMAN]] Receptor for TNFSF5/CD40LG.

== References ==

__TOC__

</StructureSection>

[[Category: Orr, C M]]

[[Category: Pearson, A R]]

[[Category: Tews, I]]

[[Category: Agonist]]

[[Category: Cd40]]

[[Category: Engineered fab]]

[[Category: Immune system]]

[[Category: Mab]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6fax is ON HOLD  until Paper Publication
+==Complex of Human CD40 Ectodomain with Lob 7.4 Fab==
+<StructureSection load='6fax' size='340' side='right' caption='[[6fax]], [[Resolution|resolution]] 2.99&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6fax]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FAX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FAX FirstGlance]. <br>
-Description:
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fax OCA], [http://pdbe.org/6fax PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fax RCSB], [http://www.ebi.ac.uk/pdbsum/6fax PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fax ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
+== Disease ==
+[[http://www.uniprot.org/uniprot/TNR5_HUMAN TNR5_HUMAN]] Defects in CD40 are the cause of immunodeficiency with hyper-IgM type 3 (HIGM3) [MIM:[http://omim.org/entry/606843 606843]]. A rare immunodeficiency syndrome characterized by normal or elevated serum IgM levels with absence of IgG, IgA, and IgE. It results in a profound susceptibility to bacterial infections.<ref>PMID:11675497</ref>
+== Function ==
+[[http://www.uniprot.org/uniprot/TNR5_HUMAN TNR5_HUMAN]] Receptor for TNFSF5/CD40LG.
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Orr, C M]]
+[[Category: Pearson, A R]]
+[[Category: Tews, I]]
+[[Category: Agonist]]
+[[Category: Cd40]]
+[[Category: Engineered fab]]
+[[Category: Immune system]]
+[[Category: Mab]]