Lipase: Difference between revisions

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Line 94: Line 94:
**[[3g7n]] – Lip - ''Penicillium expansum''<br />
**[[3g7n]] – Lip - ''Penicillium expansum''<br />
**[[1tia]] - Lip – ''Penicillium camemberti''<br />
**[[1tia]] - Lip – ''Penicillium camemberti''<br />
**[[2qua]], [[2qub]] – LipA – ''Serratia marcescens''<br />
**[[2qua]], [[2qub]] – SmLipA – ''Serratia marcescens''<br />
**[[5x7k]] – SmLipB NBD <br />
**[[5nen]] – SmLipC residues 1-443 <br />
**[[2hih]] – Lip – ''Staphylococcus hyicus''<br />
**[[2hih]] – Lip – ''Staphylococcus hyicus''<br />
**[[2fx5]] – Lip – ''Pseudomonas mendocina''<br />
**[[2fx5]] – Lip – ''Pseudomonas mendocina''<br />
Line 111: Line 113:
**[[2zvd]] – PsLip - ''Pseudomonas sp.'' – open state<br />
**[[2zvd]] – PsLip - ''Pseudomonas sp.'' – open state<br />
**[[2z8x]] - PsLip – extracellular<br />
**[[2z8x]] - PsLip – extracellular<br />
**[[5xpx]] – PsLip residues 1-388<br />
**[[2zj6]], [[2zj7]] – PsLip (mutant) <br />
**[[2zj6]], [[2zj7]] – PsLip (mutant) <br />
**[[2z8z]] – PsLip(mutant) – closed state<br />
**[[2z8z]] – PsLip(mutant) – closed state<br />
**[[3lip]], [[3a6z]] - Lip - ''Pseudomonas cepacia'' – open state<br />
**[[3lip]], [[3a6z]] - Lip - ''Pseudomonas cepacia'' – open state<br />
**[[1qge]], [[1tah]] – Lip – ''Pseudomonas glumae''<br />
**[[1qge]], [[1tah]] – Lip – ''Pseudomonas glumae''<br />
**[[2w22]] – GtLip – ''Geobacillus thermocatenulatus''<br />
**[[2w22]], [[6a12]] – GtLip – ''Geobacillus thermocatenulatus''<br />
**[[5ce5]] – GtLip (mutant)<br />
**[[5ce5]] – GtLip (mutant)<br />
**[[1ji3]], [[1ku0]], [[4fmp]], [[4x6u]]– BstLip – ''Bacillus stearothermophilus''<br />
**[[1ji3]], [[1ku0]], [[4fmp]], [[4x6u]]– BstLip – ''Bacillus stearothermophilus''<br />
**[[4x71]], [[4x7b]], [[4x85]] – BstLip (mutant)<br />
**[[4x71]], [[4x7b]], [[4x85]] – BstLip (mutant)<br />
**[[1ah7]] - Lip – ''Bacillus cereus''<br />
**[[1ah7]] - Lip – ''Bacillus cereus''<br />
**[[2qxt]], [[2qxu]], [[1isp]], [[1i6w]], [[4fdm]], [[5ct5]], [[5ct6]]  - BsLip – ''Bacillus subtilis''<br />
**[[2qxt]], [[2qxu]], [[1isp]], [[1i6w]], [[4fdm]], [[5ct4]], [[5ct5]], [[5ct6]], [[5cri]]  - BsLipA – ''Bacillus subtilis''<br />
**[[3d2a]], [[3d2b]], [[3d2c]], [[1t2n]], [[1t4m]], [[3qmm]], [[3qzu]], [[4fkb]], [[5ct8]] - BsLip (mutant) <br />
**[[3d2a]], [[3d2b]], [[3d2c]], [[1t2n]], [[1t4m]], [[3qmm]], [[3qzu]], [[4fkb]], [[5ct8]], [[5ct9]], [[5cta]], [[5cur]] - BsLip (mutant) <br />
**[[2ory]] – Lip – ''Photobacterium lypoliticum''<br />
**[[2ory]] – Lip – ''Photobacterium lypoliticum''<br />
**[[2z5g]], [[2dsn]] – GzLip T1 – ''Geobacillus zalihae''<br />
**[[2z5g]], [[2dsn]] – GzLip T1 – ''Geobacillus zalihae''<br />
Line 138: Line 141:


**[[1n8s]] – hLip+colipase II<br />
**[[1n8s]] – hLip+colipase II<br />
**[[1eth]], [[1lpa]] - Lip+colipase II - pig<br />
**[[1eth]], [[1lpa]] - pLip+colipase II - pig<br />


*Hormone-sensitive-lipases (LIPE) hydrolyze the first fatty acid of the triacylglycerol substrate
*Hormone-sensitive-lipases (LIPE) hydrolyze the first fatty acid of the triacylglycerol substrate
Line 175: Line 178:
**[[1ex9]] – Lip+Rc-(Rp,Sp)-1,2-dioctylcarbamoyl-glycero-3-O-phosphonate – ''Pseudomonas aeruginosa'' <br />
**[[1ex9]] – Lip+Rc-(Rp,Sp)-1,2-dioctylcarbamoyl-glycero-3-O-phosphonate – ''Pseudomonas aeruginosa'' <br />
**[[5tgl]] – RmLip+N-hexyl-phosphonate <br />
**[[5tgl]] – RmLip+N-hexyl-phosphonate <br />
**[[1lpb]] – Lip (pig)+colipase+C11 alkyl phosphonate <br />
**[[1lpb]] – pLip + colipase+C11 alkyl phosphonate <br />
**[[3icw]] – CaLipB (mutant) +methyl hydrogen R hexylphosphonate<br />
**[[5gv5]] - CaLipB + phosphonate<br />
**[[3icw]] – CaLipB (mutant) + phosphonate<br />
**[[3a70]] – PsLip+diethyl phosphate<br />
**[[3a70]] – PsLip+diethyl phosphate<br />
**[[4glb]] – TlLip + nitrobenzaldehyde<br />
**[[4glb]] – TlLip + nitrobenzaldehyde<br />
Line 195: Line 199:
*Monoacylglycerol lipase  
*Monoacylglycerol lipase  


**[[3rm3]], [[4lhe]] - BaMAGL – ''Bacillus'' <BR />
**[[3rm3]], [[4lhe]], [[5xks]] - BaMAGL – ''Bacillus'' <BR />
**[[3hju]], [[3jw8]] - hMAGL  <BR />
**[[3hju]], [[3jw8]] - hMAGL  <BR />
**[[3rli]] – BaMAGL + PMSF<br />
**[[3rli]] – BaMAGL + PMSF<br />
**[[4ke7]], [[4ke8]], [[4ke9]] – BaMAGL + ligand<br />
**[[4ke7]], [[4ke8]], [[4ke9]] – BaMAGL + ligand<br />
**[[4ke6]], [[4kea]] – BaMAGL (mutant) + ligand<br />
**[[4ke6]], [[4kea]] – BaMAGL (mutant) + ligand<br />
**[[3jwe]], [[3pe6]], [[4uuq]] – hMAGL + inhibitor<br />
**[[3jwe]], [[3pe6]], [[4uuq]], [[6ax1]], [[6bq0]] – hMAGL + inhibitor<br />
**[[4zwn]] – yMAGL – yeast<br />
**[[4zwn]] – yMAGL – yeast<br />
**[[4zxf]] – yMAGLip + substrate analog<br />
**[[4zxf]] – yMAGLip + substrate analog<br />
**[[6eic]] – MAGLip – ''Mycobacterium tuberculosis''<br />
**[[5xk2]] – MAGLip – ''Aespergillus oryzae''<br />


*Lipase with substrate bound at active site
*Lipase with substrate bound at active site