2dc3: Difference between revisions
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'''Crystal structure of human cytoglobin at 1.68 angstroms resolution''' | '''Crystal structure of human cytoglobin at 1.68 angstroms resolution''' | ||
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[[Category: Sugimoto, H.]] | [[Category: Sugimoto, H.]] | ||
[[Category: Yoshizato, K.]] | [[Category: Yoshizato, K.]] | ||
[[Category: | [[Category: Cytoglobin]] | ||
[[Category: | [[Category: Heme]] | ||
[[Category: | [[Category: Myoglobin]] | ||
[[Category: | [[Category: Oxygen storage]] | ||
[[Category: | [[Category: Oxygen transport]] | ||
[[Category: | [[Category: Riken structural genomics/proteomics initiative]] | ||
[[Category: | [[Category: Rsgi]] | ||
[[Category: | [[Category: Structural genomic]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 00:08:52 2008'' | |||
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Revision as of 21:08, 3 May 2008
Crystal structure of human cytoglobin at 1.68 angstroms resolution
Overview
Cytoglobin (Cgb) is a recently discovered member of the vertebrate haem-containing globin family. The structure of a new crystal form of wild-type human Cgb (space group C2) was determined at a resolution of 1.68 Angstrom. The results show the presence of an additional helix in the N-terminal residues (4-20) prior to the A helix and an ordered loop structure in the C-terminal region (168-188), while these extended peptides were invisible owing to disorder in the previously reported structures using a P3(2)21 crystal at a resolution of 2.4 Angstrom. A detailed comparison of the two crystal structures shows differences in the conformation of the residues (i.e. Arg84) in the haem environment owing to a different dimeric arrangement.
About this Structure
2DC3 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
High-resolution structure of human cytoglobin: identification of extra N- and C-termini and a new dimerization mode., Makino M, Sugimoto H, Sawai H, Kawada N, Yoshizato K, Shiro Y, Acta Crystallogr D Biol Crystallogr. 2006 Jun;62(Pt 6):671-7. Epub 2006, May 12. PMID:16699195 Page seeded by OCA on Sun May 4 00:08:52 2008
