6fif: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6fif is ~~ON HOLD~~

==Crystal structure of the BRI1 Gly644-Asp (bri1-6) mutant from Arabidopsis thaliana.==

~~Authors~~: ~~Hothorn~~, M., ~~Santiago~~, J., ~~Hohmann~~, U.

== Structural highlights ==

<table><tr><td colspan='2'>[[6fif]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FIF OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FIF FirstGlance].

~~Description~~: ~~Crystal structure~~ of ~~the~~ BRI1 ~~Gly644~~-~~Asp~~ (~~bri1~~-6) ~~mutant from Arabidopsis thaliana~~.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>

~~[[Category: Unreleased Structures]]~~

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fif FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fif OCA], [http://pdbe.org/6fif PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fif RCSB], [http://www.ebi.ac.uk/pdbsum/6fif PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fif ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/BRI1_ARATH BRI1_ARATH]] Receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates. Regulates, in response to brassinosteroid binding, a signaling cascade involved in plant development, including expression of light- and stress-regulated genes, promotion of cell elongation, normal leaf and chloroplast senescence, and flowering. Binds brassinolide, and less effectively castasterone, but not 2,3,22,23-O-tetramethylbrassinolide or ecdysone. May be involved in a feedback regulation of brassinosteroid biosynthesis. Phosphorylates BRI1-associated receptor kinase 1 (BAK1), Transthyretin-Like protein (TTL) and SERK1 on 'Ser-299' and 'Thr-462' in vitro. May have a guanylyl cyclase activity.<ref>PMID:10557222</ref> <ref>PMID:10938344</ref> <ref>PMID:17138891</ref> <ref>PMID:17520012</ref> <ref>PMID:18694562</ref> <ref>PMID:19124768</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Hohmann, U]]

[[Category: Hothorn, M]]

[[Category: Santiago, J]]

[[Category: ~~Hothorn, M~~]]

[[Category: Ectodomain]]

[[Category: Leucine rich repeat receptor]]

[[Category: Membrane receptor]]

[[Category: Protein binding]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6fif is ON HOLD
+==Crystal structure of the BRI1 Gly644-Asp (bri1-6) mutant from Arabidopsis thaliana.==
+<StructureSection load='6fif' size='340' side='right' caption='[[6fif]], [[Resolution|resolution]] 2.54&Aring;' scene=''>
-Authors: Hothorn, M., Santiago, J., Hohmann, U.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6fif]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FIF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FIF FirstGlance]. <br>
-Description: Crystal structure of the BRI1 Gly644-Asp (bri1-6) mutant from Arabidopsis thaliana.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3rgx|3rgx]], [[3rgz|3rgz]], [[3riz|3riz]], [[3rj0|3rj0]], [[4lsa|4lsa]], [[4m7e|4m7e]], [[4lsx|4lsx]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fif FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fif OCA], [http://pdbe.org/6fif PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fif RCSB], [http://www.ebi.ac.uk/pdbsum/6fif PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fif ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/BRI1_ARATH BRI1_ARATH]] Receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates. Regulates, in response to brassinosteroid binding, a signaling cascade involved in plant development, including expression of light- and stress-regulated genes, promotion of cell elongation, normal leaf and chloroplast senescence, and flowering. Binds brassinolide, and less effectively castasterone, but not 2,3,22,23-O-tetramethylbrassinolide or ecdysone. May be involved in a feedback regulation of brassinosteroid biosynthesis. Phosphorylates BRI1-associated receptor kinase 1 (BAK1), Transthyretin-Like protein (TTL) and SERK1 on 'Ser-299' and 'Thr-462' in vitro. May have a guanylyl cyclase activity.<ref>PMID:10557222</ref> <ref>PMID:10938344</ref> <ref>PMID:17138891</ref> <ref>PMID:17520012</ref> <ref>PMID:18694562</ref> <ref>PMID:19124768</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Hohmann, U]]
+[[Category: Hothorn, M]]
 [[Category: Santiago, J]]
-[[Category: Hothorn, M]]
+[[Category: Ectodomain]]
+[[Category: Leucine rich repeat receptor]]
+[[Category: Membrane receptor]]
+[[Category: Protein binding]]