3n8e: Difference between revisions

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==Substrate binding domain of the human Heat Shock 70kDa protein 9 (mortalin)==
==Substrate binding domain of the human Heat Shock 70kDa protein 9 (mortalin)==
<StructureSection load='3n8e' size='340' side='right' caption='[[3n8e]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='3n8e' size='340' side='right'caption='[[3n8e]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3n8e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N8E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N8E FirstGlance]. <br>
<table><tr><td colspan='2'>[[3n8e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N8E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N8E FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GRP75, HSPA9, HSPA9B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n8e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n8e OCA], [http://pdbe.org/3n8e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3n8e RCSB], [http://www.ebi.ac.uk/pdbsum/3n8e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3n8e ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n8e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n8e OCA], [https://pdbe.org/3n8e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n8e RCSB], [https://www.ebi.ac.uk/pdbsum/3n8e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n8e ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GRP75_HUMAN GRP75_HUMAN]] Implicated in the control of cell proliferation and cellular aging. May also act as a chaperone.  
[https://www.uniprot.org/uniprot/GRP75_HUMAN GRP75_HUMAN] Implicated in the control of cell proliferation and cellular aging. May also act as a chaperone.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H]]
[[Category: Large Structures]]
[[Category: Berg, S van der]]
[[Category: Arrowsmith CH]]
[[Category: Berglund, H]]
[[Category: Berglund H]]
[[Category: Bountra, C]]
[[Category: Bountra C]]
[[Category: Collins, R]]
[[Category: Collins R]]
[[Category: Edwards, A M]]
[[Category: Edwards AM]]
[[Category: Flodin, S]]
[[Category: Flodin S]]
[[Category: Flores, A]]
[[Category: Flores A]]
[[Category: Graslund, S]]
[[Category: Graslund S]]
[[Category: Hammarstrom, M]]
[[Category: Hammarstrom M]]
[[Category: Johansson, I]]
[[Category: Johansson I]]
[[Category: Karlberg, T]]
[[Category: Karlberg T]]
[[Category: Kotenyova, T]]
[[Category: Kotenyova T]]
[[Category: Moche, M]]
[[Category: Moche M]]
[[Category: Nordlund, P]]
[[Category: Nordlund P]]
[[Category: Nyman, T]]
[[Category: Nyman T]]
[[Category: Persson, C]]
[[Category: Persson C]]
[[Category: Structural genomic]]
[[Category: Schuler H]]
[[Category: Schuler, H]]
[[Category: Schutz P]]
[[Category: Schutz, P]]
[[Category: Siponen MI]]
[[Category: Siponen, M I]]
[[Category: Svensson L]]
[[Category: Svensson, L]]
[[Category: Thorsell AG]]
[[Category: Thorsell, A G]]
[[Category: Tresaugues L]]
[[Category: Tresaugues, L]]
[[Category: Wahlberg E]]
[[Category: Wahlberg, E]]
[[Category: Weigelt J]]
[[Category: Weigelt, J]]
[[Category: Welin M]]
[[Category: Welin, M]]
[[Category: Wisniewska M]]
[[Category: Wisniewska, M]]
[[Category: Van der Berg S]]
[[Category: Beta-sandwich]]
[[Category: Chaperone]]
[[Category: Helix]]
[[Category: Sgc]]
[[Category: Substrate binding domain]]
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