2dqt: Difference between revisions

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[[Image:2dqt.gif|left|200px]]
[[Image:2dqt.gif|left|200px]]


{{Structure
<!--
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The line below this paragraph, containing "STRUCTURE_2dqt", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=CPD:[1-(3-DIMETHYLAMINO-PROPYL)-3-ETHYL-UREIDO]-[4-(2,2,2-TRIFLUORO-ACETYLAMINO)-BENZYL]PHOSPHINIC+ACID-2-(2,2-DIHYDRO-ACETYLAMINO)-3-HYDROXY-1-(4-NITROPHENYL)-PROPYL+ESTER'>CPD</scene>
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|ACTIVITY=  
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|GENE=  
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|DOMAIN=
{{STRUCTURE_2dqt| PDB=2dqt  | SCENE= }}  
|RELATEDENTRY=[[2dqu|2DQU]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dqt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dqt OCA], [http://www.ebi.ac.uk/pdbsum/2dqt PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2dqt RCSB]</span>
}}


'''High resolution crystal structure of the complex of the hydrolytic antibody Fab 6D9 and a transition-state analog'''
'''High resolution crystal structure of the complex of the hydrolytic antibody Fab 6D9 and a transition-state analog'''
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==About this Structure==
==About this Structure==
2DQT is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry 1HYX. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DQT OCA].  
This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1hyx 1hyx]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DQT OCA].  


==Reference==
==Reference==
Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis., Oda M, Ito N, Tsumuraya T, Suzuki K, Sakakura M, Fujii I, J Mol Biol. 2007 May 25;369(1):198-209. Epub 2007 Mar 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17428500 17428500]
Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis., Oda M, Ito N, Tsumuraya T, Suzuki K, Sakakura M, Fujii I, J Mol Biol. 2007 May 25;369(1):198-209. Epub 2007 Mar 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17428500 17428500]
[[Category: Mus musculus]]
[[Category: Protein complex]]
[[Category: Fujii, I.]]
[[Category: Fujii, I.]]
[[Category: Ito, N.]]
[[Category: Ito, N.]]
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[[Category: Tanaka, F.]]
[[Category: Tanaka, F.]]
[[Category: Vassylyev, D G.]]
[[Category: Vassylyev, D G.]]
[[Category: catalytic antibody]]
[[Category: Catalytic antibody]]
[[Category: ester hydrolysis]]
[[Category: Ester hydrolysis]]
[[Category: esterolytic]]
[[Category: Esterolytic]]
[[Category: fab]]
[[Category: Fab]]
[[Category: immunoglobulin]]
[[Category: Immunoglobulin]]
 
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