4v06: Difference between revisions
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==Crystal structure of human tryptophan hydroxylase 2 (TPH2), catalytic domain== | ==Crystal structure of human tryptophan hydroxylase 2 (TPH2), catalytic domain== | ||
<StructureSection load='4v06' size='340' side='right' caption='[[4v06]], [[Resolution|resolution]] 2.63Å' scene=''> | <StructureSection load='4v06' size='340' side='right'caption='[[4v06]], [[Resolution|resolution]] 2.63Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4v06]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V06 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4V06 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4v06]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V06 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4V06 FirstGlance]. <br> | ||
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== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/TPH2_HUMAN TPH2_HUMAN]] Disease susceptibility is associated with variations affecting the gene represented in this entry. Disease susceptibility is associated with variations affecting the gene represented in this entry. Naturally occurring variants of TPH2 with impaired enzyme activity could cause deficiency of serotonin production and result in an increased risk of developing behavioral disorders. | [[http://www.uniprot.org/uniprot/TPH2_HUMAN TPH2_HUMAN]] Disease susceptibility is associated with variations affecting the gene represented in this entry. Disease susceptibility is associated with variations affecting the gene represented in this entry. Naturally occurring variants of TPH2 with impaired enzyme activity could cause deficiency of serotonin production and result in an increased risk of developing behavioral disorders. | ||
==See Also== | |||
*[[Hydroxylases 3D structures|Hydroxylases 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
[[Category: Large Structures]] | |||
[[Category: Tryptophan 5-monooxygenase]] | [[Category: Tryptophan 5-monooxygenase]] | ||
[[Category: Arrowsmith, C]] | [[Category: Arrowsmith, C]] | ||
Revision as of 11:01, 26 February 2020
Crystal structure of human tryptophan hydroxylase 2 (TPH2), catalytic domain
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