6c2n: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6c2n is ~~ON HOLD until Paper Publication~~

==Crystal structure of HCV NS3/4A double mutant variant Y56H/D168A in complex with danoprevir==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6c2n]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C2N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6C2N FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TSV:(2R,6S,12Z,13AS,14AR,16AS)-6-[(TERT-BUTOXYCARBONYL)AMINO]-14A-[(CYCLOPROPYLSULFONYL)CARBAMOYL]-5,16-DIOXO-1,2,3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-HEXADECAHYDROCYCLOPROPA[E]PYRROLO[1,2-A][1,4]DIAZACYCLOPENTADECIN-2-YL+4-FLUORO-2H-ISOINDOLE-2-CARBOXYLATE'>TSV</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6c2n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c2n OCA], [http://pdbe.org/6c2n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6c2n RCSB], [http://www.ebi.ac.uk/pdbsum/6c2n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6c2n ProSAT]</span></td></tr>

</table>

__TOC__

</StructureSection>

[[Category: Matthew, A N]]

[[Category: Schiffer, C A]]

[[Category: Drug resistance]]

[[Category: Hepatitis c virus]]

[[Category: Hydrolase]]

[[Category: Hydrolase-hydrolase inhibitor complex]]

[[Category: Ns3/4a protease]]

[[Category: Protease inhibitor]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6c2n is ON HOLD  until Paper Publication
+==Crystal structure of HCV NS3/4A double mutant variant Y56H/D168A in complex with danoprevir==
+<StructureSection load='6c2n' size='340' side='right' caption='[[6c2n]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6c2n]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C2N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6C2N FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TSV:(2R,6S,12Z,13AS,14AR,16AS)-6-[(TERT-BUTOXYCARBONYL)AMINO]-14A-[(CYCLOPROPYLSULFONYL)CARBAMOYL]-5,16-DIOXO-1,2,3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-HEXADECAHYDROCYCLOPROPA[E]PYRROLO[1,2-A][1,4]DIAZACYCLOPENTADECIN-2-YL+4-FLUORO-2H-ISOINDOLE-2-CARBOXYLATE'>TSV</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6c2n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c2n OCA], [http://pdbe.org/6c2n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6c2n RCSB], [http://www.ebi.ac.uk/pdbsum/6c2n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6c2n ProSAT]</span></td></tr>
+</table>
+__TOC__
+</StructureSection>
+[[Category: Matthew, A N]]
+[[Category: Schiffer, C A]]
+[[Category: Drug resistance]]
+[[Category: Hepatitis c virus]]
+[[Category: Hydrolase]]
+[[Category: Hydrolase-hydrolase inhibitor complex]]
+[[Category: Ns3/4a protease]]
+[[Category: Protease inhibitor]]