6fia: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Structure of the human LINE-1 ORF1p coiled coil domain== | |||
<StructureSection load='6fia' size='340' side='right' caption='[[6fia]], [[Resolution|resolution]] 2.65Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6fia]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FIA FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2yko|2yko]], [[2ykp|2ykp]], [[2ykq|2ykq]], [[2w7a|2w7a]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fia OCA], [http://pdbe.org/6fia PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fia RCSB], [http://www.ebi.ac.uk/pdbsum/6fia PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fia ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/LORF1_HUMAN LORF1_HUMAN]] Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. May function as a nucleic acid chaperone binding its own transcript and therefore preferentially mobilizing the transcript from which they are encoded.<ref>PMID:11158327</ref> <ref>PMID:21937507</ref> <ref>PMID:8945518</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Khazina, E]] | |||
[[Category: Weichenrieder, O]] | |||
[[Category: Coiled coil]] | |||
[[Category: Genome evolution]] | |||
[[Category: Nucleic acid chaperone]] | |||
[[Category: Retrotransposition]] | |||
[[Category: Rna binding protein]] | |||
[[Category: Rnp]] | |||
Revision as of 06:42, 28 March 2018
Structure of the human LINE-1 ORF1p coiled coil domain
| ||||||||||||
