5z96: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5z96 is ~~ON HOLD~~

==Structure of the mouse TRPC4 ion channel==

~~Authors~~: ~~Duan~~, J., Li, Z., Li, J.~~, Zhang, J~~.

== Structural highlights ==

<table><tr><td colspan='2'>[[5z96]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z96 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Z96 FirstGlance]. <br>

~~Description: Structure of the mouse TRPC4 ion channel~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LPP:2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL+HEXADECANOATE'>LPP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5z96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z96 OCA], [http://pdbe.org/5z96 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5z96 RCSB], [http://www.ebi.ac.uk/pdbsum/5z96 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5z96 ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/TRPC4_MOUSE TRPC4_MOUSE]] Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Has also been shown to be calcium-selective (By similarity). May also be activated by intracellular calcium store depletion. Trpc4 deficient mice lack a store-operated calcium entry in endothelial cells.<ref>PMID:11175743</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Duan, J]]

[[Category: Li, J]]

[[Category: Li, Z]]

~~[[Category: Li, J]]~~

[[Category: Zhang, J]]

[[Category: Cryoem]]

[[Category: Membrane protein]]

[[Category: Mouse full length trpc4]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5z96 is ON HOLD
+==Structure of the mouse TRPC4 ion channel==
+<StructureSection load='5z96' size='340' side='right' caption='[[5z96]], [[Resolution|resolution]] 3.28&Aring;' scene=''>
-Authors: Duan, J., Li, Z., Li, J., Zhang, J.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5z96]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z96 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Z96 FirstGlance]. <br>
-Description: Structure of the mouse TRPC4 ion channel
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LPP:2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL+HEXADECANOATE'>LPP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5z96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z96 OCA], [http://pdbe.org/5z96 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5z96 RCSB], [http://www.ebi.ac.uk/pdbsum/5z96 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5z96 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/TRPC4_MOUSE TRPC4_MOUSE]] Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Has also been shown to be calcium-selective (By similarity). May also be activated by intracellular calcium store depletion. Trpc4 deficient mice lack a store-operated calcium entry in endothelial cells.<ref>PMID:11175743</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Duan, J]]
+[[Category: Li, J]]
 [[Category: Li, Z]]
-[[Category: Li, J]]
 [[Category: Zhang, J]]
+[[Category: Cryoem]]
+[[Category: Membrane protein]]
+[[Category: Mouse full length trpc4]]