5o5i: Difference between revisions
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==Robo1 Ig5== | ==Robo1 Ig5== | ||
<StructureSection load='5o5i' size='340' side='right' caption='[[5o5i]], [[Resolution|resolution]] 3.01Å' scene=''> | <StructureSection load='5o5i' size='340' side='right'caption='[[5o5i]], [[Resolution|resolution]] 3.01Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5o5i]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5o5i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O5I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5O5I FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.01Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5o5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o5i OCA], [https://pdbe.org/5o5i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5o5i RCSB], [https://www.ebi.ac.uk/pdbsum/5o5i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5o5i ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ROBO1_HUMAN ROBO1_HUMAN] Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development.<ref>PMID:10102268</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Aleksandrova | [[Category: Large Structures]] | ||
[[Category: Avilov | [[Category: Aleksandrova N]] | ||
[[Category: Gutsche | [[Category: Avilov SV]] | ||
[[Category: Kandiah | [[Category: Gutsche I]] | ||
[[Category: McCarthy | [[Category: Kandiah E]] | ||
[[Category: Petoukhov | [[Category: McCarthy AA]] | ||
[[Category: Seiradake | [[Category: Petoukhov MV]] | ||
[[Category: Seiradake E]] | |||
