Art:Ebola GP fusion loop: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Alice Clark (talk | contribs) No edit summary |
Alice Clark (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:January2017.png| | [[Image:January2017.png|400 px|right]] | ||
'''Behind the Artwork and the Protein Structure''' | '''Behind the Artwork and the Protein Structure''' | ||
| Line 16: | Line 16: | ||
Once the tip of the fusion loop has inserted into the host membrane, GP2, including the fusion loop, undergoes a huge change in conformation. The post-fusion conformation of GP2 (PDB entry 1ebo) is vastly different to that before membrane fusion and shows that the fusion loop becomes helical and moves to the vicinity of the viral membrane, likely dragging the host membrane with it and effecting membrane fusion. | Once the tip of the fusion loop has inserted into the host membrane, GP2, including the fusion loop, undergoes a huge change in conformation. The post-fusion conformation of GP2 (PDB entry 1ebo) is vastly different to that before membrane fusion and shows that the fusion loop becomes helical and moves to the vicinity of the viral membrane, likely dragging the host membrane with it and effecting membrane fusion. | ||
[[Category: PDB Art]] | |||
