Nucleoplasmin: Difference between revisions
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The activation of NP is by strong destabilization of the pentamer, probably due to electrostatic repulsion. The NP needs compact and stable structure so he can accumulate negative charges that weakens its quaternary interactions, and its required for its biological function. | The activation of NP is by strong destabilization of the pentamer, probably due to electrostatic repulsion. The NP needs compact and stable structure so he can accumulate negative charges that weakens its quaternary interactions, and its required for its biological function. | ||
==3D structures of nucleoplasmin== | |||
====3D structures of nucleoplasmin==== | |||
[[1k5j]] – XlNpl core – ''Xenopus laevis'' | [[1k5j]] – XlNpl core – ''Xenopus laevis'' | ||
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[[1ee5]], [[1ejy]] –XlNpl nuclear localization peptide + karyopherin-a | [[1ee5]], [[1ejy]] –XlNpl nuclear localization peptide + karyopherin-a | ||
== References == | ==== References ==== | ||
<references/> | <references/> | ||
2. Taneva SG1, Muñoz IG, Franco G, Falces J, Arregi I, Muga A, Montoya G, Urbaneja MA, Bañuelos S. Activation of nucleoplasmin, an oligomeric histone chaperone, challenges its stability.Biochemistry. 2008 Dec 30;47(52):13897-906. PMID:19055325 DOI:10.1021/bi800975r | 2. Taneva SG1, Muñoz IG, Franco G, Falces J, Arregi I, Muga A, Montoya G, Urbaneja MA, Bañuelos S. Activation of nucleoplasmin, an oligomeric histone chaperone, challenges its stability.Biochemistry. 2008 Dec 30;47(52):13897-906. PMID:19055325 DOI:10.1021/bi800975r | ||
