5ybz: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==High resolution structure of complement C1q-like protein 3 C1q domain== | |||
<StructureSection load='5ybz' size='340' side='right' caption='[[5ybz]], [[Resolution|resolution]] 1.71Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5ybz]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YBZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YBZ FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ybz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ybz OCA], [http://pdbe.org/5ybz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ybz RCSB], [http://www.ebi.ac.uk/pdbsum/5ybz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ybz ProSAT]</span></td></tr> | ||
[[ | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/C1QL3_MOUSE C1QL3_MOUSE]] May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Plays a role in glucose homeostasis. Via AMPK signaling pathway, stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, reduces the expression of gluconeogenic enzymes G6PC and PCK1 and hence decreases de novo glucose production.<ref>PMID:21262840</ref> <ref>PMID:21378161</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Li, Z]] | [[Category: Li, Z]] | ||
[[Category: Liu, H]] | [[Category: Liu, H]] | ||
[[Category: Xu, F]] | |||
[[Category: Signaling protein]] | |||
