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==S1 nuclease from Aspergillus oryzae with unoccupied active site==
==S1 nuclease from Aspergillus oryzae with unoccupied active site==
<StructureSection load='5fb9' size='340' side='right' caption='[[5fb9]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='5fb9' size='340' side='right'caption='[[5fb9]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5fb9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspor Aspor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FB9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FB9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5fb9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_oryzae_RIB40 Aspergillus oryzae RIB40]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FB9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FB9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5fba|5fba]], [[5fbb|5fbb]], [[5fbc|5fbc]], [[5fbd|5fbd]], [[5fbf|5fbf]], [[5fbg|5fbg]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nucS, AO090001000075 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=510516 ASPOR])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fb9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fb9 OCA], [https://pdbe.org/5fb9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fb9 RCSB], [https://www.ebi.ac.uk/pdbsum/5fb9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fb9 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aspergillus_nuclease_S(1) Aspergillus nuclease S(1)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.30.1 3.1.30.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fb9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fb9 OCA], [http://pdbe.org/5fb9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fb9 RCSB], [http://www.ebi.ac.uk/pdbsum/5fb9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fb9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NUS1_ASPOR NUS1_ASPOR]] Hydrolyzes only single-stranded DNA and RNA without apparent specificity for bases.  
[https://www.uniprot.org/uniprot/NUS1_ASPOR NUS1_ASPOR] Hydrolyzes only single-stranded DNA and RNA without apparent specificity for bases.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aspor]]
[[Category: Aspergillus oryzae RIB40]]
[[Category: Dohnalek, J]]
[[Category: Large Structures]]
[[Category: Koval, T]]
[[Category: Dohnalek J]]
[[Category: Oestergaard, L H]]
[[Category: Koval T]]
[[Category: Endonuclease]]
[[Category: Oestergaard LH]]
[[Category: Hydrolase]]
[[Category: Zinc dependent]]
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