6cfi: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6cfi is ~~ON HOLD until Paper Publication~~

==Crystal structure of Rad4-Rad23 bound to a 6-4 photoproduct UV lesion==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6cfi]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CFI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CFI FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=T64:(6-4)PHOTOPRODUCT'>T64</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cfi OCA], [http://pdbe.org/6cfi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cfi RCSB], [http://www.ebi.ac.uk/pdbsum/6cfi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cfi ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/RAD4_YEAST RAD4_YEAST]] Involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. [[http://www.uniprot.org/uniprot/RAD23_YEAST RAD23_YEAST]] Plays a central role both in proteasomal degradation of misfolded proteins and DNA repair. Central component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol. Involved in DNA excision repair. May play a part in DNA damage recognition and/or in altering chromatin structure to allow access by damage-processing enzymes.

__TOC__

</StructureSection>

[[Category: Jeffrey, P D]]

[[Category: Min, J]]

[[Category: Dna binding protein-dna complex]]

[[Category: Dna damage repair]]

[[Category: Nucleotide excision repair]]

[[Category: Ultraviolet]]

[[Category: Xeroderma pigmentosum]]

[[Category: Xpc]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6cfi is ON HOLD  until Paper Publication
+==Crystal structure of Rad4-Rad23 bound to a 6-4 photoproduct UV lesion==
+<StructureSection load='6cfi' size='340' side='right' caption='[[6cfi]], [[Resolution|resolution]] 3.36&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6cfi]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CFI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CFI FirstGlance]. <br>
-Description:
+</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=T64:(6-4)PHOTOPRODUCT'>T64</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cfi OCA], [http://pdbe.org/6cfi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cfi RCSB], [http://www.ebi.ac.uk/pdbsum/6cfi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cfi ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/RAD4_YEAST RAD4_YEAST]] Involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. [[http://www.uniprot.org/uniprot/RAD23_YEAST RAD23_YEAST]] Plays a central role both in proteasomal degradation of misfolded proteins and DNA repair. Central component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol. Involved in DNA excision repair. May play a part in DNA damage recognition and/or in altering chromatin structure to allow access by damage-processing enzymes.
+__TOC__
+</StructureSection>
+[[Category: Jeffrey, P D]]
+[[Category: Min, J]]
+[[Category: Dna binding protein-dna complex]]
+[[Category: Dna damage repair]]
+[[Category: Nucleotide excision repair]]
+[[Category: Ultraviolet]]
+[[Category: Xeroderma pigmentosum]]
+[[Category: Xpc]]