6cn0: Difference between revisions
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==2.95 Angstrom Crystal Structure of 16S rRNA Methylase from Proteus mirabilis== | |||
<StructureSection load='6cn0' size='340' side='right' caption='[[6cn0]], [[Resolution|resolution]] 2.95Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6cn0]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CN0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CN0 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/16S_rRNA_(guanine(1405)-N(7))-methyltransferase 16S rRNA (guanine(1405)-N(7))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.179 2.1.1.179] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cn0 OCA], [http://pdbe.org/6cn0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cn0 RCSB], [http://www.ebi.ac.uk/pdbsum/6cn0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cn0 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/RMTC_PROMI RMTC_PROMI]] Specifically methylates the N(7) position of guanine 1405 in 16S rRNA. Confers resistance to various aminoglycosides, including gentamicin and kanamycin.<ref>PMID:16377684</ref> <ref>PMID:20722735</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Structural genomic]] | |||
[[Category: Evdokimova, E]] | |||
[[Category: Joachimiak, A]] | |||
[[Category: Leo, R Di]] | |||
[[Category: Minasov, G]] | |||
[[Category: Satchell, K J.F]] | |||
[[Category: Savchenko, A]] | [[Category: Savchenko, A]] | ||
[[Category: Wawrzak, Z]] | [[Category: Wawrzak, Z]] | ||
[[Category: | [[Category: Csgid]] | ||
[[Category: Transferase]] | |||
[[Category: | |||