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'''Unreleased structure'''


The entry 6fvk is ON HOLD
==Phosphotriesterase PTE_C23_3==
 
<StructureSection load='6fvk' size='340' side='right'caption='[[6fvk]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
Authors: Dym, O., Aggarwal, N., Albeck, S., Unger, T., Hamer Rogotner, S., Silman, I., Leader, H., Ashani, Y., Goldsmith, M., Greisen, P., Tawfik, D., Sussman, L.J.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6fvk]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FVK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FVK FirstGlance]. <br>
Description: Phosphotriesterase PTE_C23_3
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=E8N:1-ethyl-1-methyl-cyclohexane'>E8N</scene>, <scene name='pdbligand=E8W:2-[methoxy(methyl)phosphoryl]oxypropane'>E8W</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6fee|6fee]], [[6fef|6fef]], [[6fei|6fei]], [[6fev|6fev]], [[6ffw|6ffw]], [[6for|6for]], [[6frz|6frz]], [[6fqe|6fqe]], [[6fs3|6fs3]], [[6fu0|6fu0]], [[6fu6|6fu6]]</td></tr>
[[Category: Leader, H]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aryldialkylphosphatase Aryldialkylphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.8.1 3.1.8.1] </span></td></tr>
[[Category: Sussman, L.J]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fvk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fvk OCA], [http://pdbe.org/6fvk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fvk RCSB], [http://www.ebi.ac.uk/pdbsum/6fvk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fvk ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/OPD_BREDI OPD_BREDI]] Has an unusual substrate specificity for synthetic organophosphate triesters and phosphorofluoridates. All of the phosphate triesters found to be substrates are synthetic compounds. The identity of any naturally occurring substrate for the enzyme is unknown. Has no detectable activity with phosphate monoesters or diesters and no activity as an esterase or protease. It catalyzes the hydrolysis of the insecticide paraoxon at a rate approaching the diffusion limit and thus appears to be optimally evolved for utilizing this synthetic substrate.
__TOC__
</StructureSection>
[[Category: Aryldialkylphosphatase]]
[[Category: Large Structures]]
[[Category: Aggarwal, N]]
[[Category: Albeck, S]]
[[Category: Albeck, S]]
[[Category: Unger, T]]
[[Category: Ashani, Y]]
[[Category: Aggarwal, N]]
[[Category: Dym, O]]
[[Category: Goldsmith, M]]
[[Category: Greisen, P]]
[[Category: Greisen, P]]
[[Category: Goldsmith, M]]
[[Category: Leader, H]]
[[Category: Hamer Rogotner, S]]
[[Category: Rogotner, S Hamer]]
[[Category: Silman, I]]
[[Category: Silman, I]]
[[Category: Sussman, L J]]
[[Category: Tawfik, D]]
[[Category: Tawfik, D]]
[[Category: Ashani, Y]]
[[Category: Unger, T]]
[[Category: Dym, O]]
[[Category: Hydrolase]]
[[Category: Metalloenzyme]]
[[Category: Tim barrel]]
Retrieved from "https://proteopedia.org/6fvk"